摘要
Objective:To observe the clinical therapeutic effect and safety on cancer-related fatigue(CRF)after chemotherapy treated with the reinforcing technique of acupuncture at Qihai(气海CV6),Guanyuan(关元CV4)and bilateral Zusanli(足三里ST36)in the patients with colorectal cancer.Methods:A total of 61 cases of CRF after chemotherapy for colorectal cancer were included in the trial and randomized into a control group(30 cases)and an observation group(31 cases).The patients of the two groups all accepted the regular chemotherapy.Each duration of chemotherapy was 3 weeks.In the observation group,8 treatments with acupuncture were combined before chemotherapy and from the day 1 to 3 of chemotherapy separately,once daily,30 min in each time,for two courses totally.Acupoints included bilateral ST36,CV6 and CV4.Separately,1 day before the first cycle of chemotherapy,1 day before the second cycle of chemotherapy and in 3 weeks after the second cycle of chemotherapy,the score of Piper fatigue scale(PFS)and the score of the scale for quality of life(QOL)were adopted to evaluate the improvement degree of cancer-related fatigue.Results:Regarding PFS score,in 3-week followup after acupuncture treatment,compared with the control group,the mean value of the score of perception dimension was reduced obviously in the acupuncture treatment group,indicating the significant difference(P<0.05).Compared with the values before treatment,after acupuncture,the mean values of the scores in behavior dimension,affection dimension,perception dimension,cognition dimension and the overall score were all reduced obviously,indicating the significant differences in the treatment group(all P<0.05).But the differences were not significant in the control group in the mean values of the scores in behavior dimension,affection dimension,perception dimension and cognition dimension as well as in the overall score(all P>0.05).Regarding the score of QOL scale,compared with the control group,in the treatment group,the mean value of physical function score
基金
National Key Research and Development Plan:Research on academic viewpoints,characteristic diagnosis and treatment methods of the experiences of famous Chinese medicine physicians and the prevention and treatment of critical illness in eastern China:2018YFC1704102。
