摘要
目的:分析食管癌前病变术前活检与内镜黏膜下剥离术(ESD)术后病理结果的一致性。方法:收集65例胃镜活检为食管癌前病变并行ESD治疗患者的临床资料,对比分析手术前后病理结果差异。结果:术前胃镜活检与ESD术后病理诊断整体一致性为67.7%,术后病理升级占26.2%,术前病理较术后病理高估占6.2%。其中低级别上皮内瘤变术后病理升级占52.2%,高级别上皮内瘤变术后病理升级占11.9%。结论:食管癌前病变术前胃镜活检标本与ESD标本病理程度存在一定差异,需注意术前胃镜活检在诊断低级别上皮内瘤变的病理低估程度。
Objective:To analyze the consistency between pathological results of preoperative biopsy and pathological results after endoscopic submucosal dissection(ESD)for esophageal precancerous lesions.Methods:The clinical data of 65 patients with precancerous lesions of esophagus diagnosed by gastroscopic biopsy and treated by ESD were collected.The differences of pathological results before and after operation were compared and analyzed.Results:The overall consistency was 67.7%between preoperative gastroscopic biopsy and pathological diagnosis after ESD;postoperative pathological upgrading accounted for 26.2%,and the overestimation of preoperative pathology compared with postoperative pathology accounted for 6.2%.Among them,52.2%of low-grade intraepithelial neoplasia and 11.9%of high-grade intraepithelial neoplasia had postoperative pathological upgrading.Conclusion:There is a certain difference in the pathological degree between preoperative gastroscopic biopsy specimens and ESD specimens of esophageal precancerous lesions.Therefore,attention should be paid to the extent of pathological underestimation of preoperative gastroscopic biopsy in the diagnosis of low-grade intraepithelial neoplasia.
作者
林丽萍
刘剑雄
林楠
林海凤
黄朝忠
Lin Liping;Liu Jianxiong;Lin Nan;Lin Haifeng;Huang Chaozhong(Department of Gastroenterology,Affiliated Hospital of Putian University,Putian,Fujian 351100,China)
出处
《现代临床医学》
2021年第3期173-175,共3页
Journal of Modern Clinical Medicine
基金
福建省中青年教师教育科研项目资助(JAT190554)
莆田学院科技项目资助(2019097)。
关键词
食管癌前病变
胃镜活检
内镜黏膜下剥离术
esophageal precancerous lesions
gastroscopic biopsy
endoscopic submucosal dissection
