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氢吗啡酮联合罗哌卡因PCEA对髋关节置换术患者的镇痛效果分析

Analgesic effect of hydromorphone combined with ropivacaine PCEA in patients undergoing hip replacement
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摘要 目的 研究氢吗啡酮联合罗哌卡因硬膜外自控镇痛(PCEA)对髋关节置换术(THA)患者的镇痛效果.方法 选择2019年4月~2020年10月我院进行THA的患者100例,根据PCEA药物的不同将其分为Ⅰ组和Ⅱ组,各50例.Ⅰ组使用盐酸吗啡+罗哌卡因PCEA,Ⅱ组使用盐酸氢吗啡酮+罗哌卡因PCEA.对比两组的手术情况、镇痛情况、不良反应情况.结果 两组的手术时间、麻醉时间、出血量比较差异无统计学意义(P>0.05),Ⅱ组术后4小时、12小时、24小时的活动VAS评分低于Ⅰ组(P<0.05),Ⅱ组的不良反应总发生率24.00%低于Ⅰ组的44.00%(P<0.05).结论 氢吗啡酮联合罗哌卡因PCEA对髋关节置换术患者的镇痛效果显著,不良反应较少. Objective To study the analgesic effect of hydromorphone combined with ropivacaine for patient-controlled epidural analgesia(PCEA)in patients undergoing hip replacement(THA).Methods 100 patients with THA in our hospital from April 2019 to October 2020 were selected and divided into group Ⅰ and group Ⅱ according to different PCEA drugs,50 cases in each group.Group Ⅰ was treated with morphine hydrochloride and ropivacaine PCEA,and group Ⅱ was treated with hydromorphone hydrochloride and ropivacaine PCEA.The operation,analgesia and adverse reactions of the two groups were compared.R esu lts There was no significant difference in the operation time,anesthesia time and blood loss between the two groups(P>0.05).The VAS scores of 4 hours,12 hours and 24 hours after operation in group Ⅱ were lower than those in group Ⅰ(P<0.05),and the total incidence of adverse reactions in group Ⅱ(24.00%)was lower than that in group Ⅰ(44.00%)(P<0.05).Conclusion Hydromorphone combined with ropivacaine PCEA has significant analgesic effect on patients undergoing hip arthroplasty with less adverse reactions.
作者 许骥 黄晓俊 肖璟 Xu Ji;Huang Xiaojun;Xiao Jing(Nanxiong people’s Hospital,512400)
出处 《首都食品与医药》 2021年第7期54-55,共2页 Capital Food Medicine
关键词 氢吗啡酮 罗哌卡因 髋关节置换术 不良反应 hydromorphone ropivacaine hip replacement adverse reactions
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