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基于骨科创伤患者的下肢深静脉血栓因素及临床治疗研究 被引量:1

Study on factors and clinical treatment of lower limb deep venous thrombosis in patients with orthopaedic trauma
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摘要 目的:研究骨科创伤患者下肢深静脉血栓发生因素和临床治疗方法。方法:2015年1月-2018年12月收治骨科创伤患者86例,根据是否发生下肢深静脉血栓分为发生组和未发生组。针对发生组患者采用针对性治疗措施,分析治疗前后凝血功能指标改善情况和治疗有效率情况。结果:发生组高血压病史、糖尿病史、血栓病史发生率均明显高于未发生组,凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)水平明显低于未发生组、纤维蛋白原(FIB)水平、手术时间、年龄明显高于未发生组,差异有统计学意义(P<0.05)。发生组治疗后PT、APTT、FIB水平相较于治疗前均有明显改善,差异有统计学意义(P<0.05);临床治疗总有效率为100%。结论:骨科创伤患者手术治疗后易发生下肢深静脉血栓并发症,影响因素包括病史情况、凝血指标、手术时间、年龄等,针对发生下肢深静脉血栓并发症患者,临床需尽早给予溶栓治疗联合药物抗凝治疗,能有效改善凝血功能。 Objective:To study the factors and clinical treatment of lower extremity deep venous thrombosis(DVT)in patients with orthopedic trauma.Methods:From January 2015 to December 2018,86 patients with orthopedic trauma were selected.According to the occurrence of lower limb deep venous thrombosis,patients were divided into the two groups:the occurrence group and the non-occurrence group.Targeted treatment measures were adopted for patients in the occurrence group,and the improvement of blood coagulation function index and the effective rate of treatment before and after treatment were analyzed.Results:The incidences of hypertension,diabetes and thrombosis in the occurrence group were significantly higher than those in the non-occurrence group,while the levels of prothrombin time(PT)and activated partial thromboplastin time(APTT)in the occurrence group were significantly lower than those in the non-occurrence group,and the levels of fibrinogen(FIB),operation time and age in the occurrence group were significantly higher than those in the non-occurrence group,the difference was statistically significant(P<0.05).After treatment,the levels of PT,APTT and FIB in the occurrence group were significantly improved as compared with those before treatment,the difference was statistically significant(P<0.05).The effective rate of clinical treatment was 100%.Conclusion:Patients with orthopedic trauma are prone to lower limb deep venous thrombosis complications after surgical treatment,and the influencing factors include medical history,blood coagulation index,operationtime,age and so on.For patients with complications of deep venous thrombosis of lower extremities,thrombolytic therapy combined with drug anticoagulation therapy should be given as soon as possible,which can effectively improve the blood coagulation function.
作者 向君华 谭屏 胡敏娟 Xiang Junhua;TanPing;HuMinjuan(No.921 Hospital of Joint Logistics Support Force Hospital,Hunan Changsha 410000)
机构地区 联勤保障部队第
出处 《中国社区医师》 2021年第14期101-102,105,共3页 Chinese Community Doctors
关键词 骨科创伤 下肢 深静脉血栓 Orthopedic Trauma Lower limbs Deep venous thrombosis
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