摘要
目的对介入治疗下肢动脉硬化闭塞症患者相关危险因素进行讨论分析,探讨这些危险因素与介入治疗疗效的相关性。方法选择普宁市人民医院2017年1月至2019年1月诊断为下肢动脉硬化闭塞症并接受介入治疗的患者80例作为研究对象,男59例,女21例,年龄(57.4±2.5)岁,回顾性分析上述患者住院期间的临床资料,总结患者既往高血压、糖尿病病史等危险因素,术后随访12个月,分析患者术后血管通畅率与这些危险因素的相关性。结果患者在术后随访12个月后血管平均通畅率[髂动脉65.00%(52/80)、股动脉71.25%(57/80)、腘动脉及以下血管61.25%(49/80)]明显低于术后即刻的通畅率[髂动脉96.25%(77/80)、股动脉97.50%(78/80)、腘动脉及以下血管97.50%(78/80)],差异有统计学意义(均P<0.05)。单因素分析显示,吸烟、高血压、高胆固醇血症、糖尿病及冠心病是术后复发的独立危险因素(均P<0.05)。多因素回归分析显示,糖尿病、高血压、吸烟、高胆固醇血症及冠心病是术后复发的独立危险因素(OR=2.752、1.954、2.381、2.127、2.762,均P<0.05)。结论影响下肢动脉硬化闭塞症介入治疗术后复发的相关危险因素包括高血压、高胆固醇血症、糖尿病、冠心病等,因此在采取一定措施控制血糖、血脂以及戒烟的手段能减少术后复发。
Objective To discuss and analyze the relevant risk factors of patients with arteriosclerosis obliterans on their lower extremities,and to explore the correlation between these risk factors and the efficacy of interventional therapy.Methods From January,2017 to January,2019,80 patients who were diagnosed with arteriosclerosis obliterans on their lower extremities and received interventional therapy at Puning People's Hospital were selected as research objects.The patients'clinical data during hospitalization were retrospectively analyzed.The risk factors such as history of hypertension and diabetes were summarized.The patients were followed up for 12 months after operation.The correlation between postoperative vascular patency rate and these risk factors was analyzed.Results The average blood vessel patency rates of iliac,femoral,and popliteal arteries were 65.00%(52/80),71.25%(57/80),and 61.25%(49/80)after the 12-month follow-up,and were 96.25%(77/80),97.50%(78/80),and 97.50%(78/80)immediately after surgery,with statistical differences(all P<0.05).Univariate analysis showed that smoking,hypertension,hypercholesterolemia,diabetes,and coronary heart disease were independent risk factors for postoperative recurrence(all P<0.05).Multivariate regression analysis showed that diabetes,hypertension,smoking,hypercholesterolemia,and coronary heart disease were independent risk factors for postoperative recurrence(OR=2.752,1.954,2.381,2.127,and 2.762;all P<0.05).Conclusions The risk factors that affect the recurrence of arteriosclerosis obliterans on lower extremities after interventional therapy include hypertension,hypercholesterolemia,diabetes,coronary heart disease,etc.Therefore,taking certain measures to control blood sugar and blood lipids and smoking cessation can reduce postoperative recurrence.
作者
张卓敏
李承志
张艳
Zhang Zhuomin;Li Chengzhi;Zhang Yan(Puning City People's Hospital,Puning 515300,China;Department of Interventional Vascular Diseases,First Hospital,Jinan University,Guangzhou 510630,China)
出处
《国际医药卫生导报》
2021年第7期1037-1039,共3页
International Medicine and Health Guidance News
关键词
介入治疗
下肢动脉粥样硬化闭塞症
高血压
高胆固醇血症
糖尿病
冠心病
Interventional treatment
Atherosclerosis obliterans on lower extremities
Hypertension
Hypercholesterolemia
Diabetes
Coronary heart disease
