摘要
目的研究社会支持对新确证的HIV感染者/AIDS患者(people living with human immunodeficiency virus/acquired immunodeficiency syndrome,PLWHA)抑郁合并创伤后应激障碍(posttraumatic stress disorder,PTSD)的影响。方法对2016年10月至2019年2月在武汉市金银潭医院艾滋病治疗门诊就诊的新确证PLWHA进行一对一的问卷调查,调查内容包括一般人口学特征及确证前HIV高危行为史,社会支持、抑郁和PTSD情况。抑郁合并PTSD的患者为P+D组,无抑郁无PTSD的患者为N组,采用SPSS 21.0进行统计分析,卡方检验、t检验和秩和检验比较两组变量之间的差异,多因素Logistic回归分析抑郁合并PTSD的影响因素。结果调查的320例PLWHA中,抑郁合并PTSD的患者(P+D组)72例(22.50%),无抑郁无PTSD的患者(N组)161例(50.31%),两组的性别(χ^(2)=9.84)、感染途径(χ^(2)=11.16)、是否使用过毒品(χ^(2)=30.00)构成比差异有统计学意义(均P<0.05),社会支持总分[(30.64±10.90)分,(25.51±8.55)分]、客观社会支持[(7.20±3.08)分,(5.76±2.24)分]、主观社会支持[(16.70±6.87)分,(14.04±5.61)分]、社会支持利用度[(6.74±2.59)分,(5.71±2.60)分]的评分均差异有统计学意义(t=3.56,3.57,2.88,2.81,均P<0.05)。Logistic回归分析显示,男性(β=-1.48,OR=0.23,95%CI=0.09~0.61)是PLWHA抑郁合并PTSD的保护因素,低水平社会支持(β=1.40,OR=4.05,95%CI=1.36~12.10)是PLWHA抑郁合并PTSD的危险因素。结论PLWHA人群抑郁合并PTSD的患病率较高,应当注重性别和社会支持对PLWHA抑郁合并PTSD的影响。
Objective To study the effect of social support on depression-posttraumatic stress disorder(PTSD)comorbidity among people living with human immunodeficiency virus/acquired immunodeficiency syndrome(PLWHA).Methods Using questionnaire to one-to-one investigate the newly-diagnosed PLWHA in Wuhan Jingyintan Hospital HIV/AIDS clinic from October 2016 to February 2019.The content of the questionnaire included general demographic characteristics,HIV-related high-risk behaviors before diagnosis,social support,depression and PTSD.Patients with depression and PTSD were collected as P+D group.Patients without depression or PTSD were collected as N group.The statistical software was SPSS 21.0.Chi-square test,t test and rank sum test were used to compare the differences between the two groups,and multivariate Logistic regression analysis was used to identify the influencing factors of depression combined with PTSD.Results Among 320 PLWHA,72 subjects(22.50%)had depression with PTSD(P+D group),161 subjects(50.31%)had neither depression nor PTSD(N group).Between the two groups,the differences of constituent ratios of gender(χ^(2)=9.84),routes of infection(χ^(2)=11.16),whether ever used drug(χ^(2)=30.00)were statistically significant(all P<0.05).There were statistically significant differences in the scores of social support((30.64±10.90)vs(25.51±8.55)),objective social support((7.20±3.08)vs(5.76±2.24)),subjective social support((16.70±6.87)vs(14.04±5.61))and utility of social support((6.74±2.59)vs(5.71±2.60)(t=3.56,3.57,2.88,2.81,all P<0.05).The results of Logistic analysis revealed that gender as male(β=-1.48,OR=0.23,95%CI=0.09-0.61)was protective factor for depression co-occuring with PTSD,while lower level of social support(β=1.40,OR=4.05,95%CI=1.36-12.10)was a risk factor.Conclusion The prevalence of depression co-occuring with PTSD in PLWHA is high.The influence of gender and social support should be paid more attention to PLWHA.
作者
罗莉
曹琳
许骏
胡荣
阮连国
王夏
Luo Li;Cao Lin;Xu Jun;Hu Rong;Ruan Lianguo;Wang Xia(Department of HIV/AIDS Prevention and Control,Wuhan Centers for Disease Prevention and Control,Wuhan 430024,China;HIV/AIDS Treatment Clinic,Wuhan Jinyintan Hospital,Wuhan 430013,China)
出处
《中华行为医学与脑科学杂志》
CAS
CSCD
北大核心
2021年第4期310-314,共5页
Chinese Journal of Behavioral Medicine and Brain Science
基金
武汉市卫健委重点项目(WG16B02)。
关键词
HIV感染者/AIDS患者
抑郁
创伤后应激障碍
社会支持
影响因素
People living with human immunodeficiency virus/acquired immunodeficiency syndrome
Depression
Posttraumatic stress disorder
Social support
Influencing factors
