肛周脓肿经三间隙引流术后发生肛瘘的影响因素分析被引量：6

Influencing factors of anal fistula in perianal abscess after three-cavity clearance

导出

摘要目的分析肛周脓肿患者三间隙引流术(TCC)后发生肛瘘的影响因素,为肛周脓肿患者TCC术后拟定早期干预方案提供参考。方法抽取2018年7月至2020年1月于河南科技大学第一附属医院接受TCC治疗的93例肛周脓肿患者为研究对象,于术后2个月参照相关标准评估肛周脓肿患者肛瘘发生情况;设计基线资料调查问卷,收集患者基线资料并记录,纳入可能的影响因素,经Logistic回归分析找出肛周脓肿患者TCC术后肛瘘发生的影响因素。结果93例肛周脓肿患者TCC术后发生肛瘘18例,发生率为19.35%;经单因素分析后建立多元回归模型行多因素分析结果显示,肛周脓肿病史、肠道菌致病、C反应蛋白(CRP)过表达、白细胞介素8(IL-8)过表达均是肛周脓肿患者TCC术后发生肛瘘的影响因素(OR>1,P均<0.05)。结论肛周脓肿患者TCC术后肛瘘发生风险高,可能与肛周脓肿病史、肠道菌致病、CRP过表达、IL-8过表达有关,临床应重视有上述风险因素的肛周脓肿患者TCC术后早期预防、干预,以期降低肛周脓肿患者TCC术后肛瘘发生率。 Objective To analyze the influencing factors of anal fistula in patients with perianal abscess after three-cavity clearance(TCC),and to provide a reference for early intervention plan of perianal abscess patients after TCC.Methods A total of 93 patients with perianal abscess who received TCC treatment in the First Affiliated Hospital of Henan Science and Technology University from July 2018 to January 2020 were selected as the research objects.Two months after surgery,the incidence of anal fistula in patients with perianal abscess was assessed according to relevant standards.The baseline data questionnaire was designed to collect and record the baseline data of patients.And the possible influencing factors were inputted into the Logistic analysis to identify the influencing factors of anal fistula in patients with perianal abscess after TCC.Results Among 93 patients with perianal abscess,18 cases developed anal fistula after TCC,the incidence rate was 19.35%.According to multivariate regression analysis based on univariate analysis,the history of perianal abscess,intestinal bacteria as cause of disease,overexpression of C-reactive protein(CRP),and overexpression of interleukin-8(IL-8)were all influencing factors for anal fistula after TCC in patients with perianal abscess(OR>1,all P<0.05).Conclusions Patients with perianal abscess have a high risk of anal fistula after TCC,which may be related to the history of perianal abscess,intestinal bacterial as cause of disease,CRP overexpression,and IL-8 overexpression.Clinical attention should be paid to the early prevention and intervention of patients with perianal abscess and with the above-mentioned risk factors after TCC,in order to reduce the incidence of anal fistula after treatment.

作者叶鹏飞杨会举何新立李辰王浩印 Ye Pengfei;Yang Huiju;He Xinli;Li Chen;Wang Haoyin(Department of Anorectal,the First Affiliated Hospital of Henan Science and Technology University,Luoyang 471003,China;the Third Affiliated Hospital of Henan Traditional Chinese Medicine University,Zhengzhou 450008,China;Henan Science and Technology University,Luoyang 471003,China)

机构地区河南科技大学第一附属医院肛肠科河南中医药大学第三附属医院河南科技大学

出处《中国实用医刊》 2021年第5期14-17,共4页 Chinese Journal of Practical Medicine

基金全国中医药创新骨干人才培训项目(2019128)。