摘要
目的进展性脑梗死患者超敏C反应蛋白(hs—CRP)、D-二聚体、同型半胱氨酸(Hcy)的临床应用价值。方法2019年5—12月,依照中华医学会第4届全国脑血管病学术会议制定的标准,方便选取该院神经内科住院的急性脑梗死患者82例分为进展组和非进展组,其中进展性脑梗死43例为进展组,非进展性脑梗死39例为非进展组,健康体检人员40名作为对照组。分别检测D-二聚体、hs—CRP、HCY含量。结果对照组、非进展组、进展组的hs-CRP分别为(2.09±0.41)、(6.05±3.02)、(15.90±3.52)mg/L;D-二聚体分别为(0.31±0.15)、(1.39±0.58)、(2.95±0.89)mg/L;Hcy分别为(8.43±2.48)、(18.50±5.05)、(25.70±5.79)μg/mL。进展组、非进展组血清hs—CRP、D-二聚体、Hcy水平与对照组比较差异有统计学意义(P<0.05);进展组血清hs—CRP、D-二聚体、Hcy水平与非进展组比较差异有统计学意义(P<0.05)。结论联合监测hs—CRP、D-二聚体、Hcy水平,能够预判脑梗患者的病情变化,对进展性脑梗死的预防、监测和治疗有重大意义。
Objective The clinical value of high-sensitivity C-reactive protein(hs-CRP),D-dimer and homocysteine(Hcy)in patients with progressive cerebral infarction.Methods From May to December 2019,according to the standards established by the 4th National Cerebrovascular Disease Academic Conference of the Chinese Medical Association,82 patients with acute cerebral infarction hospitalized in the department of neurology of the hospital were divided into progressive and non-progressive groups,among them,43 with progressive cerebral infarction were in the progressive group,39 with non-progressive cerebral infarction were in the non-progressive group,and 40 healthy physical examiners served as the control group.Detected the content of D-dimer,hs-CRP,and Hcy respectively.Results The hs-CRP of the control group,non-progressive group,and progressive group were(2.09±0.41)mg/L,(6.05±3.02)mg/L,(15.90±3.52)mg/L,respectively;D-dimer were(0.31±0.15)mg/L,(1.39±0.58)mg/L,(2.95±0.89)mg/L;Hcy were(8.43±2.48)μg/mL,(18.50±5.05)μg/mL,(25.70±5.79)μg/mL.Respectively.The serum levels of hs-CRP,D-dimer,and Hcy in the progression group and the non-progressive group were different from those in the control group,the difference was statistically significant(P<0.05);the serum hs-CRP,D-dimer,and Hcy levels in the progression group were compared with the non-progressive group.The difference was statistically significant(P<0.05).Conclusion The combined monitoring of hs-CRP,D-dimer,and Hcy levels can predict the changes in patients with cerebral infarction,and is of great significance for the prevention,monitoring and treatment of progressive cerebral infarction.
作者
邱军
QIU Jun(Department of Laboratory Medicine,Zoucheng Hospital of Traditional Chinese Medicine,Zoucheng,Shandong Province,273500 China)
出处
《中外医疗》
2021年第9期31-33,共3页
China & Foreign Medical Treatment
关键词
进展性脑梗死
超敏C反应蛋白
D-二聚体
同型半胱氨酸
临床应用
Progressive cerebral infarction
High-sensitivity C-reactive protein
D-dimer
Homocysteine
Clinical application
