摘要
目的通过分析药品不良反应(ADR)的发生特点及相关因素,为临床合理用药提供依据。方法收集医院2013年1月—2016年12月上报的有效ADR报表进行统计分析。结果228例ADR中,0~9岁儿童患者ADR发生率较高(占40.79%);引起ADR最常见的给药途径为静脉给药(62.3%);引起ADR最多见的药物为抗感染药物;ADR临床表现以皮肤损害最常见。结论抗感染药物是ADR监测的重点药物,儿童是ADR监测重点人群,静脉给药是ADR监测重点给药途径,皮肤病变及其附件病变是提示ADR发生的重要信号。
Objective To analyze occurrence,characteristics and related factors of 228 cases of adverse drug reactions(ADRs)in our hospital,to provide evidence for clinical rational drug use.Methods From January 2013 to December 2016 in our hospital,228 ADR cases were analyzed retrospectively.Results In 228 ADR cases,patients under 9 years old had higher incidence of ADRs(40.79%,respectively);ADR cases caused by intravenous administration were most common(62.3%).ADRs were mainly caused by anti-infectively.Clinical features of ADRs were dominated by damages of skin.Conclusion Medical staff must strengthen monitoring on ADRs of anti-infective,and ADRs in Children,and intravenous administration.Skin lesions and their appendages are the important signals to prompt the occurrence of ADR.
作者
吴丹
WU Dan(Department of Pharmacy,Chongqing Wanzhou District Maternal and Child Health Hospital,Chongqing 404000,China)
出处
《中国继续医学教育》
2021年第15期157-160,共4页
China Continuing Medical Education
关键词
药品不良反应
分析
用药监测
合理用药
静脉内滴注
抗菌药
adverse drug reaction
analysis
drug monitoring
rational drug use
intravenous drip
antibacterials
