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HBO联合去骨瓣减压术对颅脑损伤患者运动功能及血清BDNF、NSE、S100β蛋白的影响 被引量:1

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摘要 目的探究高压氧疗法(HBO)联合去骨瓣减压术对颅脑损伤患者运动功能及血清脑源性神经营养因子(BDNF)、神经元特异性烯醇化酶(NSE)、S100β蛋白水平的影响。方法按照随机数字表法将2018年6月至2020年11月揭西县人民医院收治的颅脑损伤180例患者分为对照组和研究组,各90例。对照组患者采取去骨瓣减压术治疗,研究组患者在对照组的基础上联合HBO治疗,1个疗程为10d,1疗程结束后休息3d,共治疗3个疗程。比较两组患者治疗前后意识障碍程度和格拉斯哥昏迷量表(GCS)评分、Fugl-Meyer运动功能评分与神经功能指标水平。结果与治疗前比,治疗后两组患者意识障碍为轻度占比、GCS评分、Fugl-Meyer上肢、下肢及总评分均升高,研究组高于对照组;两组患者障碍程度为中度、重度占比,血清BDNF、NSE、S100β蛋白水平均下降,研究组患者意识障碍程度为中度占比、血清BDNF、NSE、S100β蛋白水平均低于对照组(均P<0.05)。结论 HBO联合去骨瓣减压术治疗可减轻颅脑损伤患者意识障碍和昏迷程度,促进运动功能恢复,改善神经功能。
出处 《现代医学与健康研究电子杂志》 2021年第7期34-36,共3页 Modern Medicine and Health Research
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