摘要
目的研究早产儿视网膜病变(ROP)自然消退儿童的视功能发育情况。方法回顾性收集ROP自然消退儿童238例(476眼)为观察组,并根据检查时年龄分为3~≤4岁组72例(144眼),4~≤5岁组65例(130眼),5~≤6岁组101例(202眼)。以同期未发生ROP的儿童262例(524眼)作为对照组,其中3~≤4岁组89例(178眼),4~≤5岁组82例(164眼),5~≤6岁组91例(182眼)。测量并比较两组的三个不同年龄段儿童的屈光状态、眼部生物学参数和黄斑中心凹视网膜厚度。结果两组屈光状态分布、眼部生物学参数(眼轴、前房深度除外)和黄斑中心凹视网膜厚度比较差异均无统计学意义(P>0.05)。不同年龄段组内比较,球镜度数、眼轴、前房深度、晶状体厚度、黄斑中心凹视网膜厚度差异有统计学意义(P<0.05)。结论ROP自然消退儿童3~6岁的屈光状态、眼部生物学参数和黄斑中心凹视网膜厚度与无ROP儿童无显著差异,均以正视和远视为主,眼球发育未受明显影响。应重视ROP自然消退儿童是否存在视功能异常,并应加强成长过程中的视功能监测与治疗,以最大程度保护视功能发育。
Objective To study the development of visual function in children with spontaneous regression of retinopathy of prematurity(ROP).Methods A total of 238 children with spontaneous regression of ROP(476 eyes)were retrospectively collected as the observation group.According to the ages of the patients at the time of examination,they were divided into 3-≤4 years old group(n=72,144 eyes),4-≤5 years old group(n=65,130 eyes),and 5-≤6 years old group(n=101,202 eyes).A total of 262 children(524 eyes)without ROP in the same period were taken as the control group,including 89 cases(178 eyes)of the 3-≤4 years old group,82 cases(164 eyes)of the 4-≤5 years old group,and 91 cases(182 eyes)of the 5-≤6 years old group.The refractive status,biological parameters and macula central foveal thickness of the children′eyes at different ages were measured and compared between the two groups.Results There were no statistically significant differences in the refractive status,biological parameters(except axial length and anterior chamber depth)and macula central foveal thickness of the eyes between the two groups(P>0.05).Among the different age groups,there were statistically significant differences in the diopter of spherical power,axial length,anterior chamber depth,lens thickness and macular foveal retinal thickness(P<0.05).Conclusion Compared with the children without ROP,the children with spontaneously regressed ROP have no significant differences in the refractive status,biological parameters and macula central foveal thickness of the eyes from age 3 to 6.They are mainly emmetropia and hyperopia,and the development of eyeballs is not significantly affected.Attention should be paid to the existence of visual dysfunction in children with spontaneous regression of ROP,and the monitoring and treatment of visual function should be strengthened during their growth process to protect the development of visual function to the greatest extent.
作者
孙光华
满滕滕
张楠
王自冠
刘军洋
孙振静
博文
SUN Guang-hua;MAN Teng-teng;ZHANG Nan(Department of Ophthalmology, Maternity and Child Health Care Hospital of Zaozhuang, Shandong 277100, China)
出处
《中国临床新医学》
2021年第4期376-379,共4页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
山东省医药卫生科技发展计划项目(编号:2016WS0720)。
关键词
儿童
早产儿视网膜病变
视功能
Children
Retinopathy of prematurity(ROP)
Visual function
