摘要
冠状动脉粥样硬化性心脏病(简称,冠心病)是全球高度重视的一种心血管疾病。无创冠状动脉CT造影(CCTA)与有创冠状动脉造影(ICA)是临床诊断冠心病最常用的两种影像学手段。但两种检查方式仅可从解剖学角度对冠状动脉是否存在狭窄与狭窄程度进行评价,无法从血流灌注角度对冠状动脉影响心肌血供进行有效评价。因此,单一使用狭窄程度评价心肌缺血并不可靠。现阶段,ICA在评估心肌缺血的罪犯血管与病变方面,特别是造影中的临界病变,均存在判断困难。最新冠状动脉影像学中表明,冠状动脉CT血管成像(CCTA)能够评估其解剖学狭窄,但无法准确判定冠状动脉狭窄,特别在临界病变中是否产生对应心肌缺血。目前,临床对冠状动脉狭窄是否产生功能性缺血主要将血流储备分数(FFR)作为金标准,但FFR具有创伤性检查,且检查费用高昂,在临床上未得到广泛使用。由此,在冠状动脉CT的血流储备分数(FFRCT)基础下,结合无创条件功能与解剖学在诊断冠心病中具有至关重要的意义。
Coronary heart disease(CHD)is regarded as a kind of cardiovascular disease.Non-invasive coronary CT angiography(CCTA)and invasive coronary angiography(ICA)are the two most commonly used imaging methods in clinical diagnosis of coronary heart disease.However,the two methods can only be used to evaluate the degree of stenosis and stenosis of coronary artery from the angle of anatomy,and can not effectively evaluate the effect of coronary artery on myocardial blood supply from the angle of blood perfusion.therefore,single use of stenosis to evaluate myocardial ischemia is not reliable.At the present stage,ICA have judgmental difficulties in evaluating the blood vessels and lesions of the criminals with myocardial ischemia,especially the critical lesions in the angiography Hard.Recent coronary imaging has shown that coronary CT vascular imaging(CCTA)can assess its anatomical stenosis,but can not accurately determine whether coronary stenosis,especially in critical lesions,produces corresponding myocardial ischemia.At present,whether clinical coronary artery stenosis produces functional ischemia mainly uses blood flow reserve fraction(FFR)as the gold standard,but FFR has a traumatic examination,and the examination is expensive and has not been widely used clinically.Therefore,combining non-invasive condition function and anatomy with blood flow reserve fraction(FFRCT)in coronary CT is very important in the diagnosis of coronary heart disease is summarized as follows.
作者
韩长瑞
朱运刚
李艳艳
兰东
HAN Chang-rui;ZHU Yun-gang;LI Yan-yan;LAN Dong(Department of Radiology,Tianjin TEDA Hospital,Tianjin 300457)
出处
《中国医疗器械信息》
2021年第7期44-44,83,共2页
China Medical Device Information
