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中风醒脑液治疗后循环缺血性眩晕临床研究 被引量:6

Clinical Study on Zhongfeng Xingnao Solution for Treating Posterior Circulation Ischemic Vertigo
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摘要 目的观察中风醒脑液治疗后循环缺血性眩晕患者的临床疗效。方法选取80例后循环缺血性眩晕的患者,按1∶1的比例用随机数字表法分为对照组和治疗组,对照组予以西医基础治疗,治疗组予以中风醒脑液联合西医基础治疗,治疗疗程为2周,对比观察两组患者的中医证候总积分,左右椎动脉、基底动脉的平均血流速度和血管搏动指数、同型半胱氨酸、美国国立卫生研究院卒中量表(NIHSS)评分以及临床疗效。结果治疗组的临床总有效率明显高于对照组(P <0.05);治疗2周后,治疗组左右椎动脉、基底动脉的平均血流速度均显著高于对照组(P <0.05),治疗组左右椎动脉、基底动脉的血管搏动指数均显著低于对照组(P <0.05);治疗组的中医证候总积分明显低于对照组(P <0.05);治疗组同型半胱氨酸含量明显低于对照组(P <0.05),治疗组NIHSS评分明显低于对照组(P <0.05)。结论中风醒脑液联合西医基础治疗更能有效改善患者的脑供血和降低同型半胱氨酸水平,改善神经功能缺损,更能有效改善患者的中医证候,提高临床疗效。 Objective:To explore the clinical efficacy of Zhongfeng Xingnao Solution on patients with posterior circulation ischemic vertigo.Methods:Eighty patients with posterior circulation ischemic vertigo were selected and divided into a control group and a treatment group according to 1∶1 ratio with a random number table method.The control group was given basic medical treatment and the treatment group was given Zhongfeng Xingnao Solution combined with basic treatment.The course of treatment was 2 weeks.The total scores of TCM syndromes,the average blood flow velocity and vascular pulsatility index of the left and right vertebral artery and basilar artery,homocysteine(Hcy),NIHSS scores and clinical efficacy of the two groups of patients were compared and observed.Results:The total clinical efficacy of the treatment group was significantly better than that of the control group(P<0.05);before treatment,the differences in the average blood flow velocity and vascular pulsatility index of the left and right vertebral artery and basilar artery between the two groups did not show statistical significance(P>0.05);after 2 weeks of treatment,the average blood flow velocity of the left and right vertebral artery and basilar artery in the treatment group was significantly higher than that of the control group(P<0.05),and the vascular pulsatility index of the left and right vertebral artery and basilar artery in the treatment group was significantly lower than that of the control group(P<0.05).Before treatment,the difference in the total scores of TCM syndromes between the two groups did not show a statistical difference;after 2 weeks of treatment,the total scores of TCM syndromes in the treatment group were significantly lower than those in the control group.Before treatment,the difference of Hcy content in the two groups did not show any statistical difference;after 2 weeks of treatment,the content of Hcy in the treatment group was significantly lower than that in the control group.Before treatment,the NIHSS scores of the two gr
作者 黎辉 郭铁 武紫晖 于白莉 Li Hui;Guo Tie;Wu Zihui;Yu Baili(Chongqing Beibei District Hospital of Traditional Chinese Medlicine,Chongqing 400700,China)
出处 《中国中医急症》 2021年第4期629-632,共4页 Journal of Emergency in Traditional Chinese Medicine
基金 全国中医药创新骨干人才培训项目[国中医药人教函(2019)128号] 国家中医重点专科脑病专科建设项目(ZK2301NB079)。
关键词 后循环缺血 眩晕 中风醒脑液 核心病机 临床观察 Posterior circulation ischemia Vertigo Zhongfeng Xingnao Solution Core pathogenesis Clinical observation
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