摘要
目的分析甘肃省肿瘤登记地区2009—2015年肝癌发病和死亡流行特征,为制定肝癌防治策略提供依据。方法按照全国肿瘤登记中心制定的审核方法收集甘肃省10个肿瘤登记点上报的数据作为样本数据,描述甘肃省肝癌发病和死亡分布情况,按地区(城市/农村)、性别、年龄进行分层,计算肝癌发病与死亡粗率、中国人口标化率(简称中标率)、世界人口标化率(简称世标率)、累积率,以及发病和死亡的时间变化趋势。结果2009—2015年甘肃省肿瘤登记地区肝癌新发病例7457例,粗发病率为19.63/10万,中标率为17.36/10万,世标率为19.56/10万,居全部恶性肿瘤发病顺位第3位;死亡病例3279例,粗死亡率为16.48/10万,中标率为15.04/10万,世标率为17.36/10万,居全部恶性肿瘤死亡顺位第4位。肝癌发病率和死亡率均随年龄增长而上升,在85+年龄组达到高峰,呈现农村高于城市、男性高于女性的特点。甘肃省2009—2015年肝癌发病率呈上升趋势,APC为2.5%(t=1.0,P=0.4);死亡率呈下降趋势,APC为-3.7%(t=-1.1,P=0.3)。结论甘肃省肿瘤登记地区肝癌发病率呈上升趋势,而死亡率呈下降趋势,农村地区和男性人群是重点干预对象。
ObjectiveTo analyze the epidemiological characteristics of liver cancer incidence and mortality in Gansu cancer registration areas from 2009 to 2015,and to provide the evidence for the prevention and treatment strategies of liver cancer.MethodsThe data reported by 10 cancer registries in Gansu Province were collected,based on the auditing method developed by National Central Cancer Registry,as sample data to describe the distribution of incidence and mortality of liver cancer in Gansu Province.Stratified by areas(both urban and rural),gender and age groups,the crude incidence and mortality,age-standardized rate by Chinese standard population(ASR China),age-standardized rate by Segi′s population(ASR world),cumulative rate,the changing trend of incidence and mortality and other indicators were calculated.ResultsFrom 2009 to 2015,there were 7,457 new cases of liver cancer in Gansu cancer registration areas,with the crude incidence rate of 19.63/105,ASR China of 17.36/105,and ASR world of 19.56/105,ranking the third in the incidence of all malignant tumors.A total of 3,279 death cases of liver cancer,with the crude mortality rate of 16.48/105,ASR China of 15.04/105,and ASR world of 17.36/105,ranked the fourth among all malignant tumor deaths.Both the incidence and mortality of liver cancer increased with the age,and reached the peak in 85+age group which was higher in rural areas than in urban areas;and in males than in females.The incidence of liver cancer in Gansu Province from 2009 to 2015 showed an upward trend,with annual percent change(APC)of 2.5%(t=1.0,P=0.4);the mortality showed a downward trend,with APC of-3.7%(t=-1.1,P=0.3).Conclusions The incidence of liver cancer in Gansu cancer registration areas shows an increase,and the mortality shows a decrease.The rural areas and male populations are the key targets for intervention.
作者
张洁
黄瑜
丁高恒
陈莉莉
吴建军
刘玉琴
ZHANG Jie;HUANG Yu;DING Gaoheng;CHEN Lili;WU Jianjun;LIU Yuqin(Center of Disease Prevention and Control of Qilihe District,Lanzhou 730050,China;Gansu University of Chinese Medicine,Lanzhou 730020,China;Gansu Provincial Cancer Hospital,Lanzhou 730050,China)
出处
《中国癌症防治杂志》
CAS
2021年第2期132-137,共6页
CHINESE JOURNAL OF ONCOLOGY PREVENTION AND TREATMENT
关键词
肝癌
发病率
死亡率
流行病学
肿瘤登记
甘肃
Liver cancer
Incidence
Mortality
Epidemiology
Cancer registration
Gansu Province
