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丁苯酞软胶囊联合血塞通注射液治疗急性脑梗死的临床疗效及不良反应观察 被引量:8

The clinical effect and side effects of butylphthalide soft capsule combined with Xuesaitong injection in the treatment of acute cerebral infarction
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摘要 目的研究丁苯酞软胶囊联合血塞通注射液治疗急性脑梗死的临床疗效及不良反应。方法选取2018年7月至2019年9月本院收治的90例急性脑梗死患者,按照随机数表法分为联合组和参照组,各45例。参照组给予对症治疗和血塞通注射液,联合组加用丁苯酞软胶囊。比较两组患者的治疗效果及不良反应发生率。结果联合组治疗总有效率为95.6%,显著高于参照组的82.2%(P<0.05)。联合组不良反应发生率为8.8%,低于参照组的11.0%,但差异无统计学意义。结论丁苯酞软胶囊联合血塞通注射液可显著改善急性脑梗死患者的临床症状,促进患者神经功能恢复,且用药后不良反应发生率低,药物安全性较高,可在急性脑梗死的临床治疗中推广使用。 Objective To study the clinical effect of butylphthalide soft capsule combined with Xuesaitong injection in the treatment of acute cerebral infarction and to observe its adverse reactions.Methods 90 patients with acute cerebral infarction admitted to our hospital from July 2018 to September 2019 were divided into combined group and reference group,with 45 cases in each group.The reference group was given symptomatic treatment and Xuesaitong injection,the combined group was added with butylphthalide soft capsule.The treatment effect and incidence of adverse reactions were compared between the two groups.Results The total effective rate of the combined group was 95.6%,which was significantly higher than 82.2%of the reference group(P<0.05).The incidence of adverse reactions in the combined group was 8.8%,which was slightly lower than 11.0%in the reference group,but there was no significant difference between the two groups.Conclusion SBPC combined with Xuesaitong injection can significantly improve the clinical symptoms of patients with acute cerebral infarction,promote the recovery of neurological function,and the risk of adverse reactions is low,the drug safety is high,it can be used in the clinical treatment of acute cerebral infarction.
作者 黄坤 HUANG Kun(Department of Neurology,First People's Hospital of Fuzhou,Jiangxi Province,Fuzhou,Jiangxi,344000,China)
出处 《当代医学》 2021年第12期70-72,共3页 Contemporary Medicine
关键词 急性脑梗死 血塞通注射液 丁苯酞软胶囊 不良反应 Acute cerebral infarction Xuesaitong injection Butylphthalide soft capsule Adverse reactions
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