摘要
植物多糖作为一种食物来源,往往以膳食纤维的形式对人体产生有益的影响,有效抗肾脏损伤是其重要的作用之一。目前对于肾脏病的预防与治疗主要以药物为主,对于保健品、功能性食品等辅助治疗肾脏病的研究报道较少。该文从食品角度简述了植物多糖对糖尿病肾损伤、缺血再灌注肾损伤、重金属肾损伤、化学性肾损伤和药物性肾损伤的干预效果,并从直接和间接两个方面着重探讨了多糖发挥抗肾损伤的作用机制,进一步对植物多糖抗肾损伤的研究方向进行展望,以期为研发干预肾损伤的功能性食品提供参考。
As a kind of food resource,the plant polysaccharides have many beneficial effects on human body in the form of dietary fiber,and it is also an effective anti-kidney damage agent.At present,the prevention and treatment of kidney disease are mainly based on drugs.However,there are also research on the supplementary treatment of kidney diseases using health products and functional foods.In this review,the intervention effects of plant polysaccharides on diabetic kidney injury,ischemia-reperfusion kidney injury,heavy metal kidney injury,chemical kidney injury,and drug-induced kidney injury from the food point of view were briefly reviewed,and the mechanisms of polysaccharides against kidney injury from both direct and indirect aspects were mainly discussed.Finally,the research direction of plant polysaccharides against kidney damage have further prospected,so as to provide a reference for the development of functional foods for the treatment of kidney injury.
作者
刘婷
周欣
赵超
龚小见
陈华国
LIU Ting;ZHOU Xin;ZHAO Chao;GONG Xiaojian;CHEN Huaguo(Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment,Guizhou Normal University,Guiyang 550001,China;Collaborative Innovation Center for Karst Mountain Ecological Environmental Protection and Resource Utilization(Project of Education Department of Guizhou Province),Guizhou Normal University,Guiyang 550001,China;Guizhou Engineering Laboratory for Quality Control&Evaluation Technology of Medicine,Guizhou Normal University,Guiyang 550001,China;Research Center for Quality Control of Natural Medicine,Guizhou Normal University,Guiyang 550001,China.)
出处
《食品与发酵工业》
CAS
CSCD
北大核心
2021年第7期269-277,284,共10页
Food and Fermentation Industries
基金
贵州省科技计划项目(黔科合平台人才[2017]5625)
贵州省普通高等学校科技拔尖人才支持计划项目(黔教合KY字[2017]065)
贵州省高层次创新人才培养项目(黔科合人才[2015]4033)
贵州省科技计划项目(黔科合支撑[2018]2826)。
关键词
肾损伤
植物多糖
氧化应激
炎症
信号通路
kidney injury
plant polysaccharides
oxidative stress
inflammation
signalling pathway
