摘要
目的:观察补肾活血化瘀方治疗轻型膝关节骨性关节炎(肝肾亏虚型)的临床疗效。方法:选取100例膝关节骨性关节炎患者,按区组随机法分为治疗组及对照组,每组50例。对照组给予硫酸氨基葡萄糖口服,治疗组在此基础上加服补肾活血化瘀方,4周为1个疗程,治疗2个疗程。对比治疗后2组的临床疗效、膝骨关节炎严重性指数(ISOA)评分、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分及视觉模拟评分法(VAS)评分情况。结果:与治疗前比较,治疗后2组ISOA评分、WOMAC评分、VAS评分均下降(P<0.05),且治疗组低于对照组(P<0.05)。治疗组总有效率为98%,高于对照组的88%(P<0.05)。结论:补肾活血化瘀方治疗轻型膝关节骨性关节炎(肝肾亏虚型)临床疗效显著,且可以显著降低膝关节ISOA评分、WOMAC评分、VAS评分,从而改善膝关节骨性关节炎症状,进一步提高临床疗效。
Objective:To observe the clinical effect of Bushen Huoxue Huayu prescription for mild knee osteoarthritis of liver-kidney depletion type. Methods:A total of 100 cases of patients with knee osteoarthritis were divided into the treatment group and the control group according to the block random method,50 cases in each group. The control group was given oral administration of glucosamine sulphate,and the treatment group was additionally given Bushen Huoxue Huayu prescription based on the treatment of the control group. Both groups were treated for two courses,four weeks being one course. After treatment,the clinical effect,and the scores of Index of Severity for Osteoarthritis(ISOA),Western Ontario and Mcmaster Universities Osteoarthritis Index(WOMAC) and Visual Analogue Scale(VAS) in the two groups were compared. Results:After treatment, the scores of ISOA, WOMAC and VAS in the two groups were decreased when compared with those before treatment(P<0.05), and the scores in the treatment group were lower than those in the control group(P<0.05). The total effective rate was 98% in the treatment group,higher than that of 88% in the control group(P<0.05). Conclusion:Bushen Huoxue Huayu prescription for mild knee osteoarthritis of liver-kidney depletion type has significant clinical effect,which can obviously reduce the scores of ISOA, WOMAC and VAS in the knee joint so as to improve the symptoms of knee osteoarthritis and further improve the clinical effect.
作者
周洪保
王爱国
ZHOU Hongbao;WANG Aiguo
出处
《新中医》
CAS
2021年第5期112-115,共4页
New Chinese Medicine
基金
河南省科技攻关计划项目(152102310007)。
