摘要
目的探讨欣母沛治疗宫缩乏力性产后出血的效果。方法方便选取78例宫缩乏力性产后出血的患者为观察对象,研究时间为2017年7月—2018年8月,按照产妇入院时间将其分为两组,每组39例,其中命名为对照组的患者给予缩宫素治疗,另外命名为观察组的患者给予欣母沛治疗,对比两组不同治疗方式治疗有效率,对比两组患者不同时间段出血量,观察两组凝血功能变化情况及出现的不良反应。结果与对照组比较,观察组产时、产后2 h及产后24 h出血量均更少,差异有统计学意义(t=27.584、15.231、10.584,P<0.05);观察组总有效例数38例(97.44%),对照组总有效例数32例(82.05%),差异有统计学意义(χ^(2)=5.201,P<0.05);分娩后,两组患者的凝血功能指标与分娩前比较差异无统计学意义(P>0.05);组间对比分析,观察组与对照组凝血功能指标差异无统计学意义(P>0.05);观察组4例(10.26%)出现不良反应,对照组3例(7.69%)出现不良反应,差异无统计学意义(χ^(2)=0.401,P>0.05)。结论对宫缩乏力性产后出血的患者,采用欣母沛止血有着较好的止血效果,患者出血量得以显著减少,不良反应虽稍多,但不影响治疗效果,安全性得到证实,临床可进一步研究及使用。
Objective To investigate the effect of Hemabate in the treatment of postpartum hemorrhage caused by uterine asthenia.Methods 78 patients with postpartum hemorrhage due to uterine inertia were conveniently selected as the observation objects.The start and end time of the study were July 2017 and August 2018 respectively.They were divided into two groups according to the time of admission of the mothers,with 39 cases in each group,named as the control group were treated with oxytocin,and the patients named as the observation group were treated with Hemabate.The effective rates of different treatment methods in the two groups were compared,and the bleeding volume changes in coagulation function and adverse reactions of the two groups of patients at different time periods was compared.Results Compared with the control group,the observation group had less blood loss during childbirth,2 h postpartum and 24 h postpartum,the difference was statistically significant(t=27.584,15.231,10.584,P<0.05);the total effective number of patients in the observation group was 38(97.44%),and the total number of patients with effective treatment in the control group was 32(82.05%),and the statistical calculation results,the difference was statistically significant(χ^(2)=5.201,P<0.05);after delivery,the coagulation function indexes of the two groups of patients had no significant changes compared with those before delivery,the difference was not statistically significant(P>0.05);Comparative analysis between groups showed that the coagulation function indexes of the observation group and the control group was not statistically significant(P>0.05);4 cases(10.26%)of the observation group had poor performance,3 cases(7.69%)in the control group had adverse reactions,and there was no significant difference in statistical calculation results(χ^(2)=0.401,P>0.05).Conclusion In patients with postpartum hemorrhage due to weak contractions,the use of Hemabate has a good effect on hemostasis,and the bleeding volume of patients can be significantly
作者
郑艳华
胡利红
张玉妹
ZHENG Yan-hua;HU Li-hong;ZHANG Yu-mei(Department of Obstetrics,Jiangle County General Hospital,Sanming,Fujian Province,353300 China)
出处
《中外医疗》
2021年第6期73-75,共3页
China & Foreign Medical Treatment
关键词
欣母沛
宫缩乏力性产后出血
出血量
凝血功能
不良反应
Hemabate
Postpartum hemorrhage due to uterine asthenia
Bleeding volume
Coagulation function
Adverse reactions
