摘要
吡唑啉基团具有较强的蓝光发射、高的荧光量子产率及空穴传输效率,可以作为优质荧光基团参与荧光探针的设计与合成,此外,其结构中存在含孤对电子的N原子,因此也可作为识别基团承担提供结合位点的重要作用。近年来,利用吡唑啉基团的上述特点来设计合成性能优良的荧光探针已成为荧光探针研究领域中瞩目的焦点,综述了近年来具有代表性的吡唑啉类荧光探针在各种金属离子以及二氧化硫、生物硫醇、肼等小分子检测中的应用进展,并展望了其未来的发展趋势。
Pyrazoline group has excellent blue light emission,high fluorescence quantum yield and hole-transporting efficiency,so it can be used as a high-quality fluorophore to design and synthesis fluorescent probes.In addition,pyrazoline group also contains nitrogen atom with a lone pair of electrons,so it is also viewed as recognition group to play an important role on binding sites.Recently,utilizing these properties of pyrazoline group to design and synthesis better fluorescent probes has gradually become one of focuses in fluorescent detection research.Therefore,this article reviews the application progress of representative pyrazoline fluorescent probes in the detection of various metal ions and small molecules such as sulfur dioxide,biological thiols,and hydrazine in recent years,and their development tendency in the future is prospected.
作者
曹碧霞
韩正枝
刘荣
CAO Bi-xia;HAN Zheng-zhi;LIU Rong(Gansu Research Institute of Chemical Industry Co.,Ltd.,Lanzhou 730020,China;Gansu Key Laboratory of Fine Chemicals,Lanzhou 730020,China)
出处
《化学试剂》
CAS
北大核心
2021年第3期304-312,共9页
Chemical Reagents
基金
甘肃省精细化工重点实验室项目(18JR2RA021)。
关键词
吡唑啉
荧光探针
设计
检测
进展
pyrazoline
fluorescent probe
design
detection
progress
