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免疫比浊法检验血浆D-二聚体在心脑血管疾病中的临床价值体会 被引量:2

Clinical Value of Immunoturbidimetry in Detection of Plasma D-dimer in Cardiovascular and Cerebrovascular Diseases
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摘要 目的探究免疫比浊法检测血浆D-二聚体水平在心脑血管疾病中的临床应用价值。方法选取2019年11月至2020年9月如东县中医院收治的150例心脑血管疾病患者作为研究对象。共分为冠心病组、急性心肌梗死组、脑梗死组,每组50例。另选取同期在如东县中医院体检的50例健康者作为对照组。三组患者均在如东县中医院接受治疗,对四组受试者均以免疫比浊法进行血浆D-二聚体的检验,对比三组患者在治疗前及治疗后的血浆D-二聚体水平,同时比较三组患者治疗前后与对照组受试者的血浆D-二聚体水平。结果与对照组相比较,三组患者治疗前及治疗后的血浆D-二聚体水平均明显高于对照组(P<0.05);但治疗后,三组患者的血浆D-二聚体水平与治疗前比较均明显降低(P<0.05)。结论以免疫比浊法检测血浆D-二聚体水平,有着较高的临床应用价值,可用于疾病诊断参考。 Objective To explore the clinical application value of immunoturbidimetry in the detection of plasma D-dimer in cardiovascular and cerebrovascular diseases.Methods From November 2019 to September 2020,150 patients with cardiovascular and cerebrovascular diseases in Rudong Hospital of Traditional Chinese Medicine were selected as the research objects.The patients were divided into coronary heart disease group,acute myocardial infarction group and cerebral infarction group with 50 cases in each group.Another 50 healthy people in Rudong Hospital of Traditional Chinese Medicine in the same period of time were selected as the control group.Three groups of patients were treated in Rudong Hospital of Traditional Chinese medicine.The Four groups of subjects were tested for plasma D-dimer by immunoturbidimetric method.The plasma D-dimer levels of the three groups of patients before and after treatment were compared,and the plasma D-dimer levels of the three groups of patients before and after treatment were compared with those of the control group.Results The plasma D-dimer levels of the three groups of patients were significantly lower than before treatment(P<0.05);compared with the control group,the plasma D-dimer levels of the three groups of patients before and after treatment were significantly higher than those of the control group(P<0.05).Conclusion The immunoturbidimetric method for detecting plasma D-dimer levels has high clinical application value and can be used as a reference for disease diagnosis.
作者 陈晓波 唐海妹 CHEN Xiaobo;TANG Haimei(Rudong Hospital of Traditional Chinese Medicine,Nantong,Jiangsu 226400,China)
机构地区 如东县中医院
出处 《大医生》 2020年第23期135-137,共3页 Doctor
关键词 血浆D-二聚体 免疫比浊法 心脑血管疾病 plasma D-dimer immunoturbidimetry cardiovascular and cerebrovascular diseases
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