摘要
【目的】探讨乳腺癌患者全麻术后恶心呕吐(PONV)的危险因素。【方法】选择乳腺癌全身麻醉患者530例,按照患者术后是否有恶心、呕吐对530例患者的相关病史及麻醉病历分别作单因素和多因素Logistic回归分析,评价乳腺癌患者全麻术后恶心呕吐的危险因素。【结果】530例患者中,发生PONV有101例,发生率为19.06%。多因素分析发现:术前禁饮禁食时间、麻醉维持方式、术中低血压、有无使用止吐药、有无使用曲马多、术后使用阿片类药物镇痛与乳腺癌术后恶心呕吐发生相关(P<0.05)。【结论】乳腺癌患者术前长时间禁饮禁食、无使用止吐药、术中低血压、曲马多、吸入麻醉药维持麻醉、术后使用阿片类药物镇痛的术后恶心呕吐中发生率显著增高。
【Objective】To explore the risk factors for postoperative nausea and vomiting(PONV)in patients undergo⁃ing breast cancer surgery under general anesthesia.【Methods】Using univariate and multivariate logistic regression analy⁃ses,we reviewed the medical records and anesthesia history of 530 patients who underwent breast cancer surgery under general anesthesia in order to identify the associated risk factors for their PONV.【Results】Among the 530 patients,101 suffered PONV,with an incidence rate of 19.06%.Multivariate analysis revealed the risk factors associated with PONV oc⁃currence were preoperative fasting,anesthesia maintenance type,intraoperative hypotension,use of antiemetics,tramad⁃ol and postoperative opioids(P<0.05).【Conclusion】The PONV incidence is significantly higher in those breast cancer pa⁃tients with prolonged fasting before surgery,inhaled anesthetics,intraoperative hypotension or no use of antiemetics,tram⁃adol and postoperative opioids.
作者
刘婷
许冬妮
陈羽青
卢桠楠
LIU Ting;XU Dong-ni;CHEN Yu-qing;LU Ya-nan(Department of Anesthesia,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,Guangdong Province,China)
出处
《中山大学学报（医学科学版）》
CAS
CSCD
北大核心
2021年第2期302-306,共5页
Journal of Sun Yat-Sen University:Medical Sciences
基金
广东省医院药学研究基金(2020XC57)。
关键词
乳腺癌
全麻
术后恶心呕吐
危险因素
breast cancer
general anesthesia
postoperative nausea and vomiting(PONV)
risk factors
