摘要
目的:探讨室壁瘤(VA)对慢性完全闭塞病变(CTO)经皮冠状动脉介入治疗术后患者的临床特征及预后的影响。方法:连续入选2016年1月—2017年1月于我科住院并符合纳入标准的患者161例,依据心脏超声检查是否存在VA,分为VA组42例与对照组119例。收集患者的基线及相关临床资料,建立数据库,规律随访,分析预后。结果:多因素Cox风险回归模型显示,VA(HR=2.940)、左室射血分数<50%(HR=3.041)、2型糖尿病(HR=2.354)、吸烟史(HR=2.386)均为CTO患者预后不良的独立危险因素(均P<0.05)。结论:VA是CTO完全血运重建患者远期预后不良的独立危险因素之一,无创超声评估VA可能成为CTO危险分层的重要临床指标。
Objective:To investigate the effect of ventricular aneurysm(VA)on the clinical features and prognosis of patients with chronic total occlusion(CTO)after percutaneous coronary intervention(PCI).Method:A total of 161 patients who were hospitalized in our hospital and met the inclusion criteria from January 2016 to January 2017 were included,and divided into VA group(n=42)and control group(n=119)according to the existence of ventricular aneurysm(VA)detected by echocardiography.The baseline and clinical data were collected,the database was established,regular follow-up was conducted,and the prognosis was analyzed.Result:Multivariate Cox regression model showed that VA(HR=2.940),left ventricular ejection fraction<50%(HR=3.041),type 2 diabetes mellitus(HR=2.354),and history of smoking(HR=2.386)were independent risk factors for worse prognosis in CTO patients(all P<0.05).Conclusion:VA is one of the independent risk factors for poor long-term prognosis in patients with complete revascularization of CTO.Noninvasive ultrasound evaluation of VA may become an important clinical indicator for the risk stratification of CTO.
作者
刘佟
柳景华
吴铮
吕昀
李文铮
LIU Tong;LIU Jinghua;WU Zheng;LV Yun;LI Wenzheng(Department of Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing Institute of Heart Lung and Blood Vessel Diseases,Beijing,100029,China)
出处
《临床心血管病杂志》
CAS
北大核心
2021年第1期42-46,共5页
Journal of Clinical Cardiology
基金
国家自然科学基金项目(No:81970291)。
