摘要
目的:了解某三级医院门急诊第二类精神药品使用情况,促进合理用药。方法:从某三级医院信息系统提取2017~2019年门急诊第二类精神药品使用情况的数据,回顾性分析药品用量、使用金额、用药频度(defined daily dose system,DDDs)、限定日费用(defined daily cost, DDC)及排序比。随机选取2020年1~3月的门急诊第二类精神药品使用金额排名前5位的药品处方进行点评,对不合理处方进行分类统计分析。结果:2017~2019年该医院门急诊第二类精神药品共13种,药品用量及使用金额呈增长趋势,地佐辛注射液、奥沙西泮片的使用金额排序始终居前2位;艾司唑仑片、佐匹克隆片、奥沙西泮片的DDDs排序始终居前4位;酒石酸唑吡坦片的使用金额及DDDs增长较明显,2019年增至第4位;地佐辛注射液、氨酚羟考酮片的DDC较高,居前2位,而艾司唑仑片、地西泮片较低。酒石酸唑吡坦片、佐匹克隆片(胶囊)、艾司唑仑片、地西泮片、曲马多缓释片、地西泮注射液、苯巴比妥钠注射液的排序比均基本接近1.0。随机选取金额排名前5位药品各300张,共1 500张处方进行点评,总不合理处方251张,不合理率为16.73%。主要不合理处方类型为用法用量不适宜(11.95%)、特殊人群不适宜(6.37%)、联合用药不适宜(28.29%)、超处方限量(50.99%)。结论:该医院第二类精神药品的应用基本合理,后期仍需加强管理和监控,实施个体化评估,使第二类精神药品使用更加合理规范。
Objective:To investigate the application of class Ⅱ psychotropic drugs in outpatient and emergency department of our hospital, so as to promote rational drug application. Methods:The consumption amount, consumption sum, defined daily dose system(DDDs), defined daily cost(DDC) and sequence ratio of class Ⅱ psychotropic substances in our hospital during 2017-2019 were collected and analyzed.Then the top 5 prescriptions of the amount of use of class Ⅱ psychotropic drugs in outpatient were randomly selected from January to March 2020 for comment and rationality analysis. Results:During 2017-2019,the consumption sum of class Ⅱ psychotropic drugs in our hospital was in an increasing trend,the consumption sums of dizosin injection and oxazepam tablets took the top 2 positions;the DDDs of estazolam tablets, zopiclone tablets and oxazepam tablets ranked the first four. The amount of use and DDD of zolpidem tartrate tablets increased significantly, increased to the fourth in 2019;The DDC of dizosin injection and paracetamol oxycodone tablets were high, while eszolam tablets and diazepam tablets were lower. The ranking ratios of zolpidem tartrate tablets, zopiclone tablets(capsules), eszazolam tablets, diazepam tablets, tramadol sustained-release tablets, diazepam injection, phenobarbital sodium injection were all nearly 1.0. A total of 1 500 prescriptions were randomly selected,and unreasonable prescriptions accounted for 16.73%. Main types of unreasonable prescriptions include inappropriate dosage(11.95%), special population(6.37%), unsuitable drug combination(28.29%) and over-prescription limit(50.99%). Conclusion:The application of class Ⅱ psychotropic drugs in our hospital is basically reasonable, and it is still necessary to strengthen the management and monitoring in the later stage, and carry out individualized evaluation to ensure safe and effective clinical use.
作者
刘蕾
王攀
白杨
刘玥
丁海欧
孙瑞芳
LIU Lei;WANG Pan;BAI Yang;LIU Yue;DING Haiou;SUN Ruifang(Civil Aviation General Hospital,Beijing,100123)
出处
《中国药物依赖性杂志》
CAS
CSCD
2021年第1期51-56,共6页
Chinese Journal of Drug Dependence
基金
民航医学中心(民航总医院)科研基金资助项目(201927)。
关键词
第二类精神药品
使用金额
用药频度
限定日费用
处方点评
合理用药
classⅡpsychotropic drugs
consumption sum
defined daily dose
defined daily cost
prescription comments
rational drug use
