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人工肝支持系统治疗重型肝炎的临床效果研究

Study on the Clinical Effect of Artificial Liver Support System in the Treatment of Severe Hepatitis
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摘要 目的分析人工肝支持系统治疗重型肝炎的临床效果。方法于2014年1月—2019年3月研究对内科的30例重型肝炎患者进行观察分析,随机分为两组,15例对照组患者常规治疗,15例观察组患者采用人工肝支持系统治疗。对比患者疗效、肝功能指标不良反应率。结果观察组患者的治疗总有效率数据是93.33%(14例),对照组数据是53.33%(8例),观察组较高,差异有统计学意义(P<0.05);观察组治疗后TBil为(241.54±56.38)μmol/L,ALT为(96.27±61.74)U/L,AST为(105.28±72.87)U/L,CHE为(4731.64±722.64)U/L,Cr为(55.09±18.39)μmol/L,PTA为(51.83±15.27)%,各项数据较之于对照组,差异有统计学意义(t=5.874、3.725、3.058、6.337、4.490、3.786,P<0.05);观察组并发症数据较之对照组,差异无统计学意义(P>0.05)。结论人工肝支持系统治疗重型肝炎对肝功能的恢复效果比较明显,实现较高的治疗有效率,促进病情康复。 Objective To analyze the clinical effect of artificial liver support system in the treatment of severe hepatitis.Methods The study conducted observation and analysis of 30 patients with severe hepatitis in the Department of Internal Medicine of the hospital from January 2014 to March 2019 and they were randomly divided into two groups.15 patients in the control group were treated with routine treatment,15 patients in the observation group were treated with an artificial liver support system,the efficacy and liver function indexes of the patients and adrerse reactions rate were compared.Results The total effective rate of treatment for patients in the observation group was 93.33%(14 cases),and the data in the control group was 53.33%(8 cases).The observation group was higher and the difference was statistically significant(P<0.05);observation group after treatment,TBil was(241.54±56.38)μmol/L,ALT was(96.27±61.74)U/L,AST was(105.28±72.87)U/L,CHE was(4731.64±722.64)U/L,and Cr was(55.09±18.39)μmol/L,PTA was(51.83±15.27)%.Compared with the control group,the difference was statistically significant(t=5.874,3.725,3.058,6.337,4.490,3.786,P<0.05);the observation group had no statistically significant difference in the complication data compared with the control group(P>0.05).Conclusion The artificial liver support system has a more obvious effect on the recovery of liver function in the treatment of severe hepatitis.It can improve,achieve a higher,and promote the recovery of the disease.
作者 芮绍军 陈兴琼 RUI Shao-jun;CHEN Xing-qiong(Department of Internal Medicine,Yunnan Provincial Hospital of Infectious Diseases,Kunming,Yunnan Province,650000 China;Department of Infectious Diseases,Yunnan Provincial Hospital of Infectious Diseases,Kunming,Yunnan Province,650000 China)
出处 《世界复合医学》 2021年第1期80-82,共3页 World Journal of Complex Medicine
关键词 人工肝支持系统 重型肝炎 临床效果 肝功能 不良反应 Artificial liver support system Severe hepatitis Clinical effect Liver function Adverse reactions
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