摘要
敷料作为临时性替代皮肤屏障功能的医用纺织品在创伤治疗领域不可或缺,传统纺织品类敷料虽价格低廉、应用广泛,但存在无有效的抗感染功能、干燥、易与伤口发生黏连等明显缺点,不利于伤口的抗感染以及渗出液吸收。为解决这一问题,文章通过向棉织物上接枝N,N-二甲基-N-(3-(三甲氧基硅烷基)丙基)十二烷-1-氯化胺(CDMA)以赋予其抗菌性能,然后利用丙烯酸钠/改性聚六亚甲基盐酸胍(MPHMG)溶液对该织物进行浸渍处理并引发成胶,制备水凝胶基棉织物敷料。对浸渍处理前后织物的表面形貌、成分、力学性能、吸液性能、抗菌性能等进行测试,结果表明,该棉织物敷料具有良好的吸液效果以及优异的抗菌性能。
In Dressings are indispensable in the field of wound treatment as medical textiles that temporarily alternate the skin barrier capability.Although conventional textile dressings are cheap and widely used,they have obvious shortcomings such as no effective anti-infection function,dryness,and easy adhesion to the wound,which are not conducive to the anti-infection of the wound and the absorption of wound exudate.To solve this problem,N,N-dimethyl-N-(3-(trimethoxysilyl)propyl)dodecane-1-amine chloride(CDMA)was grafted onto cotton fabric to empower its antibacterial properties.Sodium acrylate/modified polyhexamethyleneguanidine hydrochloride(M-PHMG)solution was used to impregnate the fabric and initiate gelation to prepare a hydrogel-based cotton dressing.After tested and analyzed the surface morphology,composition,mechanical properties,liquid absorption performance,and antibacterial performance before and after the immersion treatment,the results indicated that this cotton dressing has a good liquid absorption effect and excellent antibacterial properties.
出处
《纺织导报》
CAS
2021年第2期64-68,共5页
China Textile Leader
基金
上海市自然科学基金项目(18ZR1400500)。
关键词
医用棉织物敷料
抗菌性
聚六亚甲基盐酸胍
长链烷基季铵盐
亲水性
medical cotton dressing
bacteria repellency
polyhexamethylene guanidine hydrochloride
long chain alkyl quaternary ammonium salt
hydrophilicity
