摘要
目的评定普罗布考加多奈哌齐给药治疗方式运用于阿尔茨海默病患者的临床治疗的干预价值。方法对2017年1月—2019年12月医院治疗的100例阿尔茨海默病患者开展两个组别干预,各个组别纳入例数50例,选取分组方式参考抛硬币方式,试验组采取普罗布考联合多奈哌齐给药治疗方式,参照组采取多奈哌齐给药治疗方式,研究给药治疗总有效率、给药治疗效果满意率、给药后不良反应发生率。结果试验组给药治疗总有效率比参照组大(P<0.05);试验组给药治疗效果满意率比参照组大(P<0.05);试验组给药后不良反应发生率比参照组低,但差异无统计学意义(P>0.05)。结论为阿尔茨海默病患者提供普罗布考加多奈哌齐给药治疗方式显现出较好临床治疗干预效果。
Objective To evaluate the clinical intervention value of probucol plus donepezil administration in patients with Alzheimer's disease.Methods Two groups of 100 patients with Alzheimer's disease treated in our hospital from January 2017 to December 2019 were conducted.Each group included 50 cases.The grouping method was selected with reference to the coin toss method.The group adopted probucol plus donepezil administration and the reference group adopted donepezil administration.The total effective rate,satisfaction rate and incidence of adverse reactions were studied.Results The total effective rate of the experimental group was higher than that of the reference group(P<0.05);the satisfaction rate of the experimental group was higher than that of the reference group(P<0.05);the incidence of adverse reactions in the experimental group was lower than that of the reference group,but the difference was not statistically significant(P>0.05).Conclusion Probucol and donepezil administration to patients with Alzheimer's disease has shown better clinical intervention effects.
作者
朱佳
陈菲
美丽班娜
姬佳妮
成娜
单梓梅
王建斌
ZHU Jia;CHEN Fei;MEI Libanna;JI Jiani;CHENG Na;SHAN Zimei;WANG Jianbin(The Third Ward of Cadre Health Center,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi Xinjiang 830000,China)
出处
《中国继续医学教育》
2021年第9期165-168,共4页
China Continuing Medical Education
基金
新疆维吾尔自治区人民医院科技引进创新项目(20170321)。
