摘要
目的:探讨变应性鼻炎(AR)患者粉尘螨皮肤点刺试验(SPT)结果阳性强度的影响因素及其SPT结果的阳性强度与其病变严重程度的相关性。方法:回顾性分析昆山市中医医院2016年6月至2018年1月收治的粉尘螨SPT结果为阳性的382例AR患者的临床资料,观察其性别、年龄及合并其他变应性疾病的种类数对其粉尘螨SPT结果阳性强度的影响,分析其粉尘螨SPT结果的阳性强度与其AR症状评分的相关性。结果:1)这些患者中不同年龄段(0〜4岁、5〜14岁、15〜29岁、30〜44岁、45〜59岁、60〜69岁)患者粉尘螨SPT结果的阳性强度相比,P<0.05(其中年龄越大的患者粉尘螨SPT结果的阳性强度越弱)。2)这些患者中男性与女性患者粉尘螨SPT结果的阳性强度相比,P>0.05。这些患者中年龄为15〜29岁或30〜44岁患者中女性患者粉尘螨SPT结果的阳性强度强于男性患者,P<0.05;其余年龄段患者中男性与女性患者粉尘螨SPT结果的阳性强度相比,P>0.05。3)这些患者中未合并其他变应性疾病的患者、合并有1种其他变应性疾病的患者、合并有2种其他变应性疾病的患者、合并有3种其他变应性疾病的患者粉尘螨SPT结果的阳性强度相比,P<0.05(其中合并其他变应性疾病种类数越多的患者粉尘螨SPT结果的阳性强度越强)。4)进行Spearman相关性分析结果的显示,这些患者粉尘螨SPT结果的阳性强度与其AR症状评分无相关性,P>0.05。结论:AR患者粉尘螨SPT结果的阳性强度与其年龄、性别、合并变应性疾病的种类数等因素有关,其粉尘螨SPT结果的阳性强度与其病变严重程度无相关性。
Objective:To investigate the influencing factors of the positive intensity of dust mite skin prick test(SPT)in patients with allergic rhinitis(AR)and the correlation between the positive intensity of SPT and the severity of the lesions.Methods:a retrospective analysis of kunshan city hospital of traditional Chinese medicine in June 2016 to January 2018 dust mites SPT results positive for the clinical data of 382 patients with AR,observe its gender,age,number of species and other allergic diseases combined effects on the dust mites SPT result positive strength,analyzes its dust mites SPT result positive strength and its the correlation of AR and symptom scores.Results:1)Compared with the positive intensity of dust mite SPT in patients of different age groups(0-4 years old,5-14 years old,15-29 years old,30-44 years old,45-59 years old,60-69 years old),P<0.05(the older the patients,the weaker the positive intensity of dust mite SPT results).2)The positive intensity of dust mite SPT in male and female patients in these patients was P>0.05.Among these patients aged 15-29 years or 30-44 years,the positive intensity of dust mite SPT in female patients was stronger than that in male patients(P<0.05).Compared with the positive intensity of dust mite SPT in male and female patients in other age groups,P BBB 00.05.3)of these patients did not merge other allergic diseases patients,1 with other allergic diseases of patients,with two other allergic diseases of patients,with three other allergic diseases patients compared to dust mites SPT result positive strength,P<0.05(including the more number of other types of allergic diseases combined dust mites SPT result of the stronger positive).4)Spearman correlation analysis showed that there was no correlation between the positive intensity of dust mite SPT and AR symptom score in these patients(P>0.05).Conclusion:The positive intensity of dust mite SPT in AR patients is related to age,gender,the number of allergic diseases and other factors,but there is no correlation between the p
作者
侯学健
蒋锐
王秀敏
王欢
祁燕
HOU Xuejian;JIANG Rui;WANG Xiumin;WANG Huan;QI Yan(Department of Otolaryngology,Kunshan Hospital of Traditional Chinese Medicine,Kunshan 215300,Jiangsu,China)