摘要
目的探讨加速时间指数(ATI)及弹性应变率比值(SR)鉴别诊断乳腺良恶性肿瘤的应用价值。方法回顾性分析120例乳腺肿瘤患者的临床资料,根据病理结果分为良性组76例(98个病灶)和恶性组44例(57个病灶),均行常规超声和超声弹性成像检查,计算并比较两组二维超声图像特征、ATI及SR值。绘制受试者工作特征(ROC)曲线分析ATI、SR值及其联合鉴别诊断乳腺恶性肿瘤的价值,计算曲线下面积(AUC)。结果良、恶性组二维超声图像特征(病灶形态、长轴方向、回声强度、内部回声是否均匀、边界情况、钙化程度、后方回声强度)比较,差异均有统计学意义(均P<0.05);恶性组ATI、SR值均高于良性组(0.18±0.05 vs.0.11±0.03,3.05±0.65 vs.2.33±0.41),差异均有统计学意义(均P<0.05)。ROC曲线分析显示,ATI、SR值鉴别诊断乳腺恶性肿瘤的AUC分别为0.842、0.813,且联合应用的AUC(0.906)高于其单独应用(均P<0.05)。结论ATI、SR值均能准确鉴别乳腺良、恶性肿瘤,两者联合应用价值更高。
Objective To explore the application value of acceleration time index(ATI)and ratio of elastic strain rate(SR)in the differential diagnosis of benign and malignant breast tumors.Methods The clinical data of 120 breast tumor patients was analyzed retrospectively.They were divided into benign group(76 cases,98 lesions)and malignant group(44 cases,57 lesions)according to the results of pathological examination.All patients were underwent conventional ultrasound and ultrasound elastography,the ATI and SR values of the two groups were calculated and compared.The receiver operating characteristic(ROC)curve was drawn to analyze the value of ATI,SR and their combination in the differential diagnosis of malignant breast tumors,the area under the curve(AUC)was calculated.Results Two-dimensional ultrasound image characteristics(lesions form,long axis direction,echo intensity,internal echo uniformity,boundary condition,calcification degree,posterior echo intensity)were compared between the two groups,the differences were statistically significant(all P<0.05).The ATI and SR values of patients in the malignant group were significantly higher than those in the benign group(0.18±0.05 vs.0.11±0.03,3.05±0.65 vs.2.33±0.41),the differences were statistically significant(both P<0.05).ROC curve analysis showed that the AUC of ATI and SR values for differential diagnosis of malignant breast tumors were 0.842 and 0.813,respectively,and the AUC(0.906)of the combined application was higher than that of the single application(both P<0.05).Conclusion Both the acceleration time index and SR show good application value in the differential diagnosis of benign and malignant breast tumors,and the combined value of the two is higher.
作者
周瑾
邢飞
樊云清
张鹭
ZHOU Jin;XING Fei;FAN Yunqing;ZHANG Lu(Department of Ultrasound,the Second People’s Hospital of Huai’an,Jiangsu 223001,China)
出处
《临床超声医学杂志》
CSCD
2021年第3期212-215,共4页
Journal of Clinical Ultrasound in Medicine
关键词
超声检查
加速时间指数
弹性应变率比值
乳腺肿瘤
良恶性
Ultrasonography
Acceleration time index
Ratio of elastic strain rate
Breast tumor,benign and malignant
