摘要
目的探讨氨磺必利治疗阴性症状为主的精神分裂症患者的临床疗效.方法将84例以阴性症状为主的精神分裂症患者按照随机数字表法分为两组,各42例.研究组给予氨磺必利治疗,对照组给予利培酮治疗,观察3个月.比较两组临床疗效,治疗前后采用威斯康星卡片分类测验评定两组患者的认知状况.结果研究组总有效率显著高于对照组(P<0.05).治疗后两组总错误数及持续错误数显著低于治疗前(P<0.01),总正确数及持续反应数显著高于治疗前(P<0.01),研究组较对照组变化更显著(P<0.01).结论氨磺必利治疗阴性症状为主的精神分裂症患者疗效显著,能改善患者的阴性症状,值得推广应用.
Objective To explore the effect of sulfamethil in the treatment of schizophrenia patients with negative symptoms.Methods 84 patients with schizophrenia with negative symptoms were randomly divided into two groups,42 cases each.The study group was treated with amisulpride,and the control group was treated with risperidone for 3 months.The clinical efficacy of the two groups was compared.The WCST was used to assess the cognitive status of the two groups before and after treatment.Results The total effective rate of the study group was significantly higher than that of the control group(P<0.05).After treatment,the total number of errors and the number o£consecutive errors in the two groups were significantly lower than before treatment(P<0.01).The total correct number and continuous response was significantly higher than before treatment(P<0.01).The study group was more significant than the control group(F<0.01).Conclusions Amisulpride is effective in the treatment of patients with schizophrenia with negative symptoms,which can improve the negative symptoms of patients and is worthy of promotion.
作者
张晓琳
任姣娜
全宏洁
Zhang Xiaolin;Ren Jiaona;Quan Hongjie(Pingdingshan Psychiatric Hospital,Pingdingshan 467000,Henan,China;不详)
出处
《临床心身疾病杂志》
CAS
2020年第1期144-145,共2页
Journal of Clinical Psychosomatic Diseases
