摘要
目的:探讨广西35~74岁壮族人群高脂血症与行为生活方式和体成分之间的相关性,筛选广西壮族人群高脂血症患者与行为生活方式和体成分相关的影响因素。方法:收集调查对象的问卷、体格检查和血生化信息。采用R语言将数据集按7:3随机分为训练集和测试集进行统计描述和分析。采用单因素t检验或卡方检验探索高脂血症与行为生活方式以及体成分之间的相关性,采用Lasso回归和二分类Logistics回归筛选高脂血症患者与行为生活方式以及体成分相关的影响因素。结果:广西壮族人群高脂血症的总体患病率约为31.6%。两个数据集多因素回归结果分别显示:男性(OR=1.49,95%CI:1.33~1.66,P<0.001;OR=1.57,95%CI:1.32~1.83,P<0.001)、吸烟(OR=1.11,95%CI:1.05~1.17,P<0.001;OR=1.14,95%CI:1.05~1.24,P=0.005)、腰围大(OR=1.03,95%CI:1.02~1.04,P<0.001;OR=1.04,95%CI:1.03~1.06,P<0.001)、心率快(均为OR=1.01,95%CI:1.01~1.02,P<0.001)是高脂血症的危险因素,而农村居住地(OR=0.69,95%CI:0.57~0.81,P<0.001;OR=0.76,95%CI:0.54~0.96,P=0.009)和身体水分率含量高(OR=0.96,95%CI:0.95~0.98,P<0.001;OR=0.94,95%CI:0.93~0.96,P<0.001)是高脂血症的保护因素。结论:广西壮族人群高脂血症患病风险较高,建议对多种危险因素并存的高危人群采取综合防治措施,控制血脂异常的发生发展。
Objective: To explore the relationship between hyperlipidemia and Behavioral lifestyle and body composition in the natural population of Zhuang nationality aged 35-74 in Guangxi. Methods: Face-to-face questionnaire survey, physical examination and blood biochemical information of Guangxi Zhuang people were collected. The data were randomly divided into training-set and test-set at a ratio of 7:3 for statistical description and analysis using R language.Univariate t test and chi-square test were used to explore the correlation between hyperlipidemia and behavioral lifestyle and body composition. The Lasso regression and binary Logistics regression were used to explore the influencing factors of behavioral lifestyle and body composition of hyperlipidemia. Results: The prevalence of hyperlipidemia in Guangxi Zhuang population was about 31.6%.Multivariate regression showed that males(OR=1.72, 95% CI: 1.33-1.66, P<0.001;OR=1.57, 95% CI: 1.32-1.83,P<0.001), smoking(OR=1.11, 95% CI: 1.05-1.17, P<0.001;OR=1.14,95% CI: 1.05-1.25, P=0.005), the larger waist circumference(OR=1.04, 95% CI: 1.02-1.04, P<0.001;OR=1.03, 95% CI: 1.03-1.06, P<0.001)and the faster heart rate(OR=1.01, 95% CI: 1.01-1.02,P<0.001)were risk factors for hyperlipidemia, while rural residence(OR=0.69, 95% CI: 0.57-0.87, P<0.001;OR=0.76, 95% CI: 0.54-0.96, P=0.009)and body water percentage(OR=0.96, 95% CI: 0.95-0.98, P<0.001;OR=0.94, 95%CI: 0.93-0.96, P<0.001)were protective factors for hyperlipidemia. Conclusion: The prevalence of hyperlipidemia in Guangxi Zhuang population is relatively high. It is suggested to take comprehensive prevention and treatment measures to control the occurrence and development of dyslipidemia in high-risk population with multiple risk factors coexisting.
作者
马晓云
刘顺
曾小云
余红平
苏莉
黄东萍
杨莉
何敏
仇小强
Ma Xiaoyun;Liu Shun;Zeng Xiaoyun;Yu Hongping;Su Li;Huang Dongping;Yang Li;He Min;Qiu Xiaoqiang(School of Public Health,Guangxi Medical University,Nanning 530021,China;Graduate School,Guangxi Medical University,Nanning 530021,China;The Affiliated Tumor Hospital of Guangxi Medical University,Nanning 530021,China;Laboratory Animal Center,Guangxi Medical University,Nanning 530021,China)
出处
《广西医科大学学报》
CAS
2021年第2期381-387,共7页
Journal of Guangxi Medical University
基金
国家重点研发计划课题资助项目(No.2017YFC0907103)。
关键词
高脂血症
行为生活方式
体成分
危险因素
保护因素
hyperlipidemia
behavioral lifestyle
body composition
risk factors
protective factors
