摘要
2型糖尿病(T2DM)是一种慢性代谢性疾病,长期高血糖导致各种并发症的发生,如肾病、心肌病等,姜黄素是中药姜黄中的活性成分,其抗氧化、抗炎、降血糖等活性使其在2型糖尿病及其慢性并发症治疗和预防中有很大的潜力。姜黄素可以延缓糖尿病的发展,改善β细胞功能,降低胰岛素抵抗等,笔者综述了姜黄素在T2DM及其慢性并发症中作用,探讨其改善T2DM的机制。
Type 2 diabetes mellitus(T2DM)is a chronic metabolic disease.High blood sugar can produce various complications,such as kidney disease and cardiomyopathy etc.Curcumin is a bioactive molecule presents in the Curcumae longae plant.Its antioxidant,anti-inflammatory and hypoglycemic activities make it have great potential in the treatment and prevention of the disease of T2DM.Research shows that curcumin delays the development of diabetes,improvesβ-cell functions and decreases insulin resistance.This paper reviewed the role of curcumin in T2DM and its chronic complications,and discussed the mechanism of curcumin in improving T2DM.
作者
许传俊
明艳林
陈良华
黄雯
XU Chuan-jun;MING Yan-lin;CHEN Liang-hua(Fujian Provincial Key Laboratory of Subtropical Plant Physiology and Biochemistry,Xiamen Key Laboratory of Subtropical Plant Physiology and Biochemistry,Fujian Institute of Subtropical Botany,Xiamen,Fujian 361006;Xiamen Overseas Chinese Subtropical Plant Introduction Garden,Xiamen,Fujian 361002)
出处
《安徽农业科学》
CAS
2021年第6期30-34,38,共6页
Journal of Anhui Agricultural Sciences
基金
厦门市科技计划项目(3502Z20182013)。
