Transcriptional output, cell-type densities, and normalization in spatial transcriptomics 被引量：1

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摘要 Dear Editor,Spatial transcriptomics(ST)makes it possible to perform RNA-seq at hundreds of precisely located spots on the surface of a histological slice(Stahl et al.,2016).Since mRNA diffusion is minimal during tissues permeabilization and mRNA capture,the transcriptome of each spot is thought to aggregate the transcriptomes of the cells it contains.

作者 Manuel Saiseletlft Joel Rodrigues-Vitoria Adrien Tourneur Ligia Craciun Alex Spinette Denis Larsimont Guy Andry Joakim Lundeberg Carine Maenhaut Vincent Detours

机构地区 IRIBHM Department of Pathology Department of Head&Neck and Thoracic Surgery Science for Life Laboratory Department of Bioengineering

出处《Journal of Molecular Cell Biology》 SCIE CAS CSCD 2020年第11期906-908,共3页 分子细胞生物学报（英文版）

关键词 al. HISTOLOGICAL hundreds

分类号 R329.2 [医药卫生—人体解剖和组织胚胎学]

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Journal of Molecular Cell Biology

2020年第11期

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Transcriptional output, cell-type densities, and normalization in spatial transcriptomics 被引量：1

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