摘要
目的分析免疫球蛋白(Ig)检验对乙型肝炎患者治疗的临床应用价值。方法选取2019年1月至2020年3月间南昌市洪都中医院收治的64例乙型肝炎患者作为研究对象,按病情严重程度将其分为轻型组(n=36)和重型组(n=28);另外选择同期在南昌市洪都中医院进行健康体检的20例健康者作为对照组,三组均给予免疫球蛋白检验,比较三组的血清IgA、IgM、IgG水平。与此同时,跟踪64例乙型肝炎患者的具体治疗情况,根据病情改善分为改善组(n=41)和未改善组(n=23),再对比两组的血清IgA、IgM、IgG以及总胆红素水平。结果经检验,重型组的血清IgA、IgM、IgG水平高于轻型组、对照组(P<0.05);轻型组的血清IgA、IgM、IgG水平高于对照组(P<0.05)。经跟踪、总结,64例乙型肝炎患者中有41例治疗后病情得到显著改善(改善组),23例治疗后未见明显有好转迹象(未改善组),改善组的血清IgA、IgM、IgG及总胆红素水平均低于未改善组(P<0.05)。结论通过血清IgA、IgM、IgG水平的检测,能有效判断乙型肝炎的病情严重程度,也能作为疾病诊断的重要标志物之一,再结合总胆红素水平,可判定疾病治疗效果,免疫球蛋白检验价值高。
Objective To analyze the clinical value of immunoglobulin(Ig)test in the treatment of hepatitis B patients.Methods A total of 64 patients with hepatitis B admitted to Nanchang Hongdu Hospital of TCM from January 2019 to March 2020 were selected as the research subjects.They were divided into the light group(n=36)and the severe group(n=28)according to the severity of the disease.In addition,20 healthy people who underwent physical examination in Nanchang Hongdu Hospital of TCM were selected as the control group during the same period.All three groups were given an immunoglobulin test.The serum IgA,IgM,and IgG levels of the three groups were compared.At the same time,the specific treatment of 64 patients with hepatitis B was followed up.They were divided into the improved group(n=41)and the unimproved group(n=23)according to their improvement.Then the serum IgA,IgM,IgG,and total bilirubin levels of the two groups were compared.Results After the test,the levels of serum IgA,IgM,and IgG in the severe group were higher than those in the light group and the control group(P<0.05).The levels of serum IgA,IgM,and IgG in the light group were higher than those in the control group(P<0.05).After follow-up and summary,41 out of 64 patients with hepatitis B were significantly improved after treatment(improvement group);23 cases showed no apparent signs of improvement after treatment(unimproved group).The serum IgA,IgM,IgG,and total bilirubin levels in the improved group were lower than those in the unimproved group(P<0.05).Conclusion The detection of serum IgA,IgM,and IgG levels can effectively determine the severity of hepatitis B and can also be used as one of the important markers of disease diagnosis.Combined with the total bilirubin level,it can determine the therapeutic effect of the disease.The immunoglobulin test is of high value.
作者
罗文燕
金玉梁
LUO Wenyan;JIN Yuliang(Department of Laboratory Medicine,Nanchang Hongdu Hospital of TCM,Nanchang 330000,China;The Third Hospital of Nanchang City,Nanchang 330000,China)
出处
《中国现代医生》
2021年第5期110-113,共4页
China Modern Doctor
