摘要
目的介绍一种对新辅助放化疗后直肠癌患者的纳米碳淋巴示踪方法。方法回顾性分析2016年1月至2020年5月河南省肿瘤医院普外科行手术治疗的88例直肠癌新辅助放化疗患者,按照术前是否采用纳米碳淋巴结示踪分为放化疗后纳米碳示踪组(观察组)和放化疗后非纳米碳示踪组(对照组)。结果观察组和对照组患者术后检出淋巴结数为[15(11-19)枚比9(5-12)枚,Z=5.227,P<0.001],差异有统计学意义;阳性淋巴结数为[0(0-0.25)枚比0(0-1)枚,2=1.199,P=0.231],差异无统计学意义;两组患者淋巴结<7枚患者比例为(0/34比18/54,χ^(2)=14.248,P<0.001),淋巴结<10枚患者比例为(4/34比29/54.χ^(2)=15.657,P<0.001),差异均有统计学意义。结论新辅助放化疗后注射纳米碳可提高直肠癌患者术后的淋巴结检出数,同时可提高淋巴结检出数≥7枚和≥10枚患者的比例,更有利于对患者预后的判断。
Objective To evaluate a nano-carbon lymphatie tracing method for patients with rctal caneer after neoadjuvant radiotherapy and chemotherapy,Method Retrospective analysis was made on 88 patients of rectal cancer undergoing neoadjuvant chemoradiation at the Department of General Surgery,He'nan Cancer Hospital from Jan 2016 to May 2020.According to whether nano-carbon lymph node was used or not,patients were divided into nanocarbon tracer group(study goup)and non-nanocarbon tracer group(control group).Results There was statistically significant in the number of havested lymph nodes between the two groups[15(11-19)u8.9(5-12),Z=5.227,P<0.001],There was no statistically significant in the number of positive lymph nodes between the two groups[0(0-0.25)vs.0(0-1),Z=1.199,P=0.231].There were significant differences in the ratio of patients with less than 7 lymph nodes(0/34 s.18/54,χ^(2)=14.248,P<0.001)and patients with less than 10 lymph nodes(4/34 s.29/54,χ^(2)=15.657.P<0.001).Conclusions The injection of nanocarbon after neoadjuvant chemoradiotherapy ean inerease the number of harvested postoperative lymph nodes and the ratio of patients with lymph nodes≥7 and≥10,which is more beneficial for prediction of the prognosis of patients.
作者
曹养辉
张习杰
刘晨宇
马鹏飞
张俊立
韩广森
赵玉洲
Cao Yanghui;Zhang Xijie;Liu Chenyu;Ma Pengfei;Zhang Junli;Han Guangsen;Zhao Yuzhou(Department of General Surgery,Affiliated Tumor Hospital of Zhenzhou University(Hernan Tumor Hospital),Zhenzhou 450008,China)
出处
《中华普通外科杂志》
CSCD
北大核心
2021年第2期90-92,共3页
Chinese Journal of General Surgery
关键词
直肠肿瘤
碳
淋巴结
肿瘤辅助疗法
Rectal neoplasms
Carbon
Lymph nodes
Neoajuvant therapy
