摘要
乙酰基呕吐毒素、葡萄糖苷基呕吐毒素、硫酸基呕吐毒素和谷胱甘肽基呕吐毒素是粮食中常见的修饰型呕吐毒素。这些修饰型真菌毒素容易逃脱检测,从而导致毒素暴露风险被低估。另外,修饰型呕吐毒素在人和动物体内会重新转化为游离型呕吐毒素和新的呕吐毒素代谢物,给人类健康带来潜在威胁。该综述对粮食中常见的修饰型呕吐毒素的产生、毒性及其代谢进行集中讨论,旨在为修饰型呕吐毒素的研究提供参考,并呼吁国家有关部门尽快制定修饰型真菌毒素安全限量标准,以保障粮食质量安全。
Acetyl deoxynivalenol,deoxynivalenol-3-glucoside,deoxynivalenol-sulfate and deoxynivalenolglutathione are common modified deoxynivalenol contaminated in grains.These modified mycotoxins are easily escaped to detect,resulting in an underestimation of the risk of mycotoxin exposure.In addition,modified deoxynivalenol can be transformed into free form and new metabolites in humans and animals,which poses a potential threat to human health.This review will focus on the occurrence,toxicity and metabolism of the common modified deoxynivalenol in grains,aiming to provide reference for the study of modified deoxynivalenol,and call on relevant national departments to formulate safety limit standards for modified mycotoxins as soon as possible to ensure grain quality and safety.
作者
汪洋
王松雪
WANG Yang;WANG Songxue(Academy of National Food and Strategic Reserves Administration,Beijing 100037,China)
出处
《食品科技》
CAS
北大核心
2021年第2期321-327,共7页
Food Science and Technology
基金
“十三五”重点研发计划专项(2017YFC1600900)
国家自然科学基金面上项目(31972605)
中央级公益性科研院所基本科研业务费专项(ZX1915)。
关键词
修饰型呕吐毒素
毒性
代谢
modified deoxynivalenol
toxicity
in vivo and in vitro metabolism
