摘要
采用硅胶柱色谱、中压色谱、Sephadex LH-20柱色谱及制备型HPLC等方法对香鳞毛蕨Dryopteris fragrans进行化学成分研究,通过1D,2D NMR,IR等波谱学方法并结合文献对分离得到的化合物进行结构鉴定。从该植物全草95%乙醇提取物中分离纯化得到2个间苯三酚类化合物,分别鉴定为2′,4′,6′-三羟基-5′-乙酸甲酯-3′-甲基-1′-丁酰酚(1)和绵马酚B(2)。其中化合物1为新化合物,命名为香蕨酚。
Two phloroglucinol compounds(1-2)were isolated and purified from 95%ethanol extract of Dryopteris fragrans through various column chromatographies on silica gel,Sephadex LH-20,medium pressure column chromatography,and preparative HPLC.Their structures were elucidated as 2′,4′,6′-trihydroxy-5′-methyl acetate-3′-methyl-1′-butyrophenone(1)and aspidinol B(2)based on their chemical and physicochemical methods and spectroscopic data.Compound 1 is a new phloroglucinol compound named"dryofraginol".
作者
朱冲冲
彭冰
曾祖平
韩旭阳
王宏
王天园
ZHU Chong-chong;PENG Bing;ZENG Zu-ping;HAN Xu-yang;WANG Hong;WANG Tian-yuan(Beijing Institute of Traditional Chinese Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China;Beijing Key Laboratory of Clinic and Basic Research with Traditional Chinese Medicine on Psoriasis(BZ0375),Beijing 100010,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2021年第2期388-390,共3页
China Journal of Chinese Materia Medica
关键词
鳞毛蕨属
香鳞毛蕨
间苯三酚衍生物
香蕨酚
Dryopteris
Dryopteris fragrans
phloroglucinol derivative
dryofraginol
