摘要
目的探讨并分析放疗联合骨肿瘤切除术对不同分期骨癌患者的临床疗效。方法选择60例骨癌患者为研究对象,根据其肿瘤分期及恶性程度分为低恶组和高恶组,两组均采用放疗联合骨肿瘤切除术进行治疗,术后采用VAS评分评估两组患者骨癌痛程度,统计两组治疗后随访6个月内局部肿瘤控制率、复发情况以及并发症发生率,并进行比较。结果①术后3 h,两组患者疼痛程度评分相比差异不具有统计学意义(P>0.05),术后1 d~2 d,低恶组患者放疗联合骨肿瘤切除术后疼痛程度评分均显著低于高恶组(P<0.05);②与低恶组相比,高恶组患者局部肿瘤控制有效率显著降低,生存期显著缩短,差异均具有统计学意义(P<0.05);③低恶组和高恶组复发率相比差异无统计学意义(P>0.05);④两组患者术后并发症相比,低恶组显著低于高恶组(P<0.05)。结论放疗联合骨肿瘤切除术对早期骨癌患者具有较好的治疗效果,术后疼痛程度和并发症降低、肿瘤控制有效率提升,从而使得患者生存期显著延长,推荐用于早期骨癌患者的临床治疗。
Objective To investigate and analyze the clinical effect of radiotherapy combined with bone cancer resection on patients with different stages of bone cancer.Methods 60 patients with bone cancer were selected as the research subjects.According to the tumor stage and malignant degree,they were divided into low-evil group and high-evil group,and both groups were treated with radiotherapy combined with bone tumor resection.Postoperative VAS score was used to assess the pain of bone cancer in the 2 groups,and the local tumor control rate,recurrence rate and complication rate within 6 months of treatment between the 2 groups were counted and compared.Results①At 3 hours after surgery,the difference in pain score between the 2 groups was not statistically significant(P<0.05);②From 1 d to 2 d after operation,the pain scores of patients in the low-evil group after radiotherapy combined with bone cancer resection were significantly lower than those in the high-evil group(P<0.05);③There was no significant difference in recurrence rate between the low-evil group and the high-evil group(P>0.05);④Compared with postoperative complications of the 2 groups of patients,the low-evil group was significantly lower than the high-evil group(P<0.05).Conclusion Radiotherapy combined with bone cancer resection has a good therapeutic effect on patients with early bone cancer.The degree of postoperative pain and complications are reduced,and the efficiency of tumor control is improved,so that the survival time of patients is significantly prolonged.It is recommended for the clinical treatment of patients with early bone cancer.
作者
韩杰
张东伟
肖锐
HAN Jie;ZHANG Dongwei;XIAO Rui(The Sixth People's Hospital of Luoyang,Luoyang,471039)
出处
《实用癌症杂志》
2021年第3期437-439,共3页
The Practical Journal of Cancer
基金
国家科技支撑计划项目(编号:2014BAI12B03)。
关键词
放疗
骨肿瘤切除术
骨癌
预后
骨癌疼痛
Radiotherapy
Bone cancer resection
Bone cancer
Prognosis
Bone cancer pain
