摘要
目的观察尼可地尔联合左卡尼汀对不稳定型心绞痛患者脂代谢水平的影响。方法118例冠心病不稳定心绞痛患者按随机数字表法将患者分为观察组(n=60例)和对照组(n=58例),对照组给予尼可地尔,观察组给与尼可地尔联合左卡尼汀治疗,30d后观察患者治疗有效率。血脂代谢及不良反应。结果观察组患者治疗有效率明显高于对照组(P<0.05),血脂中TC、TG、LDL指标改善优于对照组,差异有统计学意义(P<0.05),两组不良反应无显著差异(P>0.05)。结论联合用药能够显著改善UAP患者血脂水平,提高UAP患者治疗疗效,且不增加不良反应。
Objective To observe the effect of nicorandil combined with levocarnitine on lipid metabolism in patients with unstable angina pectoris(UAP).Methods 118 patients with UAP of coronary heart disease were divided into observation groups(n=60)and control group(n=58)by the random number table method.The control group was treated with nicorandil and the observation group was treated with nicorandil combined with levocarnitine.30 days later,the effective rate of treatment,blood lipid metabolism,and adverse reactions were observed.Results The effective treatment rate in the observation group was significantly higher than that in the control group(P<0.05).The improvement of blood lipids such as TC,TG,and LDL in the observation group was better than that in the control group(P<0.05).There were no significant differences in adverse reactions between the two groups(P>0.05).Conclusion Combined medication can significantly improve the blood lipid levels in patients with UAP patients and improve the therapeutic effects without increasing adverse reactions.
作者
李长青
王伟
张咏梅
LI Chang-qing;WANG Wei;ZHANG Yong-mei(Department of Cardiology,the Second People’s Hospital of Jiaozuo,Jiaozuo 454000,Henan Province,China)
出处
《罕少疾病杂志》
2021年第2期39-40,共2页
Journal of Rare and Uncommon Diseases
关键词
尼可地尔
左卡尼汀
不稳定型心绞痛
脂代谢
Nicorandil
Levocarnitine
Unstable Angina Pectoris
Lipid Metabolism
