摘要
目的探讨瘢痕狭窄型(Ⅳ型)气管支气管结核(TBTB)介入治疗的有效性及安全性,为临床提供循证依据。方法回顾性收集2017年1月~2019年12月重庆医科大学附属第一医院收治的43例Ⅳ型TBTB患者的临床资料,分析患者治疗情况,记录治疗前后患者狭窄处管腔直径、第1秒用力呼气容积(FEV1)实测值、mMRC评分、临床疗效及并发症发生情况。结果所有患者均使用冷冻、球囊扩张治疗;治疗后患者气道直径及FEV1实测值均高于治疗前,mMRC评分低于治疗前,差异均有统计学意义(P<0.05);气道介入治疗Ⅳ型TBTB的总有效率为81.40%,所有患者均未出现严重并发症。结论气道介入治疗对Ⅳ型TBTB总体疗效较好,但须注意安全性,尤其是使用支架治疗时,应做好相关并发症的处理。
Objective To explore the effectiveness and safety of interventional treatment for type IV(scarring stenosis)tracheobronchial tuberculosis(TBTB),and provide evidence-based evidence for clinical practice.Methods The clinical data of 43 patients with type IV TBTB admitted to the First Affiliated Hospital of Chongqing Medical University from January 2017 to December 2019 were retrospectively collected,and the treatment status of the patients was analyzed.Before and after treatment,the diameter of the lumen at the stenosis,the measured value of the forced expiratory volume in the first second(FEV1),the mMRC score,the clinical efficacy and the occurrence of complications were recorded.Results All patients were treated with cryotherapy and balloon dilatation;the measured values of airway diameter and FEV1 were higher after treatment,and the mMRC score was lower than before treatment,the difference was statistically significant(P<0.05);The total effective rate of airway interventional therapy for type IV TBTB was 81.40%,and no serious complications occurred in all patients.Conclusion Airway interventional therapy has a good overall effect on type IV TBTB,but safety must be paid attention to,especially when stents are used to treat related complications.
作者
聂箫
NIE Xiao(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)
出处
《医学信息》
2021年第5期117-119,共3页
Journal of Medical Information
基金
国家“十三五”科技重大专项(编号:2018ZX10302302003)。
关键词
Ⅳ型气管支气管结核
气道介入
第1秒用力呼气容积
TypeⅣtracheobronchial tuberculosis
Airway intervention
Forced expiratory volume in the first second
