摘要
目的比较卡贝缩宫素和麦角新碱联合缩宫素预防产后出血的治疗效果。方法选取120名足月产妇作为研究对象,按随机数字表法分为观察组和对照组,各60例。观察组给予卡贝缩宫素预防产后出血,对照组使用麦角新碱联合缩宫素治疗。记录产妇的一般信息、出血量、产后2 h和24 h血红蛋白水平的变化情况,用药前后心率、收缩压和舒张压变化及不良反应发生情况。结果观察组产妇出血量、血红蛋白水平变化显著优于对照组(P<0.05)。2组间收缩压、舒张压及心率变化无显著差异(P>0.05)。观察组产妇不良反应发生情况明显低于对照组(P<0.05)。结论卡贝缩宫素预防产后出血的效果明显优于麦角新碱与催产素联合治疗,且引起不良反应较少。
Objective To compare the effect of caebetocin and ergonovine in combination with oxytocin in preventing postpartum haemorrhage.Methods A total of 120 full-term pregnant women were selected as the research subjects and divided into observation group (Group A) and control group (Group B) according to the random number table method,with 60 cases in each group.The observation group was given carbetocin to prevent postpartum hemorrhage,while the control group was given ergonovine combined with oxytocin.The subjects’ general information,blood loss,changes in hemoglobin levels at 2 and 24 hours postpartum,changes in heart rate,systolic and diastolic blood pressure before and after medication and adverse reactions were recorded.Results There was no statistically significant difference in the general data (age,gestational week,birth weight) between the two groups of parturients.The amount of bleeding,the change in hemoglobin levels in the observation group were significantly better (P<0.05).There was no significant difference in systolic and diastolic pressure and the change in heart rate between the two groups (P>0.05).The incidence of side effects of the observation group was significantly lower (P<0.05).Conclusion The effect of carbetocin to prevent postpartum hemorrhage is more significant than ergonovine in combination with oxytocinand and less side effects are caused.The therapy is worthy of clinical application.
作者
胡宇博
王俊容
王皓莹
叶聪
HU Yubo;WANG Junrong;WANG Haoying;YE Cong(Department of Anesthesiology,China-Japan Union Hospital of Jilin University,Changchun 130033,China;Department of Obstetrics and Gynecology,China-Japan Union Hospital of Jilin University Changchun 130033,China)
出处
《长春中医药大学学报》
2021年第1期126-128,共3页
Journal of Changchun University of Chinese Medicine
基金
Twist基因在宫颈癌转移机制中的作用(3R218I293430)。
