摘要
目的观察一种含青刺果、马齿苋、滇山茶和三七的美白精华液对黄褐斑的疗效及副作用。方法选取36例黄褐斑患者,使用含上述成分的美白精华液,2次/d,早晚各一次,所有患者在治疗前、治疗4周和治疗12周后进行改良黄褐斑面积和严重指数(modified Melasma Area and Severity Index Score,mMASI)评分,皮肤图像分析系统(VISIA)拍摄图片和CK皮肤无创检测仪监测数据,并记录治疗过程中发生的不良反应。结果外用美白精华液治疗4周后和12周后mMSAI评分、CK的黑素值和血红素值均低于治疗前分值,且差异具有统计学意义(P<0.01),VISIA图像显示治疗12周后斑点、棕色斑和红色区均较治疗前改善明显。结论外用含青刺果、马齿苋、滇山茶和三七的美白精华液对黄褐斑治疗疗效确切,且无不良反应,是治疗黄褐斑的一种安全有效的手段之一。
Objective To investigate the efficacy and side effects of a new type of whitening extract,including prinsepiautilis,portulacaoleracea,Chinacamellia,sanchi.Methods 36 patients with melasma were treated with whitening cream containing the above ingredients for 2 times a day.Before treatment,4 weeks and 12 weeks after treatment,all patients were treated with mMASI,VISIA and CK skin noninvasive detector monitoring data,and adverse reactions occurred during the treatment were recorded.Results After 4 weeks and 12 weeks,the scores of mMSAI,melanin and hemoglobin were lower than those before treatment,and the difference was statistically significant(P<0.01).VISIA images showed that spots,brown spots and red areas improved significantly after treatment for 12 weeks.Conclusion Topical use of whitening extractincluding prinsepiautilis,portulacaoleracea,Chinacamellia,and sanchi is effective and safe for melasma,and there were no adverse reactions.It is a safe and effective way to treat melasma.
作者
陆雯丽
陈军
夏栩琼
LU Wen-li;CHEN Jun;XIA Xu-qiong(Department of Dermatology,Department of Laser and Aesthetic Medicine,The Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China)
出处
《皮肤病与性病》
2020年第6期789-792,共4页
Dermatology and Venereology
