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失眠对老年冠心病患者的炎性反应递质及心肌酶的影响 被引量:2

Effects of Insomnia on Inflammatory Mediators and Myocardial Enzymes in Elderly Patients with Coronary Heart Disease
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摘要 目的:探究失眠对老年冠心病实验室检测指标的影响。方法:选取2017年5月至2019年8月本院心内科收治的急性心肌梗死患者110例作为研究对象,采用匹兹堡水睡眠量表将患者分为对照组(n=48)和观察组(n=62),跟踪随访分析心梗1个月后2组炎性反应递质指标及心肌酶的差异。结果:观察组较对照组的胸痛次数显著增多(P<0.001),实验室检测结果表明观察组较对照组的CRP及心肌酶均显著升高(P<0.001)结论:失眠等睡眠障碍会明显影响老年冠心病患者的心肌酶谱及CRP,增加心绞痛风险。 Objective:To explore the influence of insomnia on laboratory detection indexes of elderly coronary heart disease.Methods:Patients with coronary heart disease were divided into control group and study group using the Pittsburgh Water Sleep Scale.Follow-up analysis was performed to analyze the differences of inflammatory mediators and myocardial enzymes between the two groups after 1 month of myocardial infarction.Results:The number of chest pain in the study group was significantly higher than that in the control group(P<0.001).The laboratory test results showed that the CRP and myocardial enzymes in the study group were significantly higher than the control group(P<0.001).Conclusion:Sleep disorders such as insomnia can significantly affect myocardial enzymes and CRP,and increase the risk of angina pectoris in elderly patients with coronary heart disease.
作者 吴嘉诚 林翠琴 朱小东 WU Jiacheng;LIN Cuiqin;ZHU Xiaodong(1 Zhangzhou Hospital of traditional Chinese medicine of Fujian Province,Zhangzhou 363000,China;No.909 Hospital of joint service support force,No.1 Hospital of traditional Chinese medicine,Zhangzhou 363020,China)
出处 《世界睡眠医学杂志》 2021年第1期61-62,共2页 World Journal of Sleep Medicine
关键词 失眠冠心病 心绞痛 心肌酶 炎性反应递质 Insomnia coronary heart disease Angina pectoris Myocardial enzymes Inflammatory mediator
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