摘要
目的探讨子宫内膜癌采用术中快速冰冻病理检查的临床价值。方法回顾性分析2015年1月至2019年12月苏州市相城人民医院收治的108例子宫内膜癌患者为研究对象,术前均经分段诊断性刮宫方法确诊为子宫内膜癌,给予手术治疗并行术中快速冰冻病理切片检查,然后根据石蜡病理检查结果,判断术中快速冰冻病理检查结果。结果本组的108例患者中,经术后病理检查,90例为子宫内膜样腺癌,占83.33%,3例为透明细胞癌,占2.78%,11例为浆液性癌,占10.19%,4例为其他类型,占3.70%,而术中冰冻检查对子宫内膜样腺癌、透明细胞癌、浆液性癌以及其他类型的符合率分别为94.44%(85/90)、100.0%(3/3)、72.73%(8/11)、100.0%(4/4),总符合率为92.59%(100/108);同时,根据国际妇产科学联合会(FIGO)标准分期,I期、II期、III期、IV期分别为83例,11例,12例,2例,而术中冰冻检查对I期、Ⅱ期、Ⅲ期、Ⅳ期符合率分别为69.88%(58/83)、72.73%(8/11)、83.33%(10/12)、100.0%(2/2),总符合率为72.22%(78/108)。根据肿瘤细胞分级(Grade,G),78例为G1,占72.22%,12例为G2,占11.11%,18例为G3,占16.67%。同时,石蜡切片和快速冰冻病理检查比较有统计学意义(P<0.05)。结论快速冰冻病理检查在子宫内膜癌术中对组织学分级的诊断准确率不高,但是对肌层浸润深度,尤其是≥1/2肌层浸润深度具有较高的准确率,可以作为评估肌层浸润深度的一个检查方法。
Objective To investigate the clinical value of rapid intraoperative freezing pathological examination for endometrial carcinoma.Methods Retrospective analysis from January 2015 to December 2019,Xiangcheng People's Hospital treated 108 examples of intrauterine membrane cancer patients as the research object,preoperative diagnosis were diagnosed by piecewise curettage method for endometrial cancer,given surgery parallel intraoperative rapid frozen pathological biopsy,and then according to the results of the paraffin wax pathologic examination judgment intraoperative frozen pathological examination results quickly.Results Group of 108 cases of patients,the postoperative pathological examination,90 cases of endometrial adenocarcinoma,accounted for 83.33%,3 cases of clear cell carcinoma,2.78%,11 cases of serous carcinoma,accounted for 10.19%,4 cases for other types,accounted for 3.70%,and intraoperative frozen sample inspection of endometrial adenocarcinoma,clear cell carcinoma,serous carcinoma and other types of coincidence rate was 94.44%(85/90),100.0%(3/3),72.73%(8/11)and 100.0%(4/4),the total coincidence rate was 92.59%(100/108);At the same time,according to the international federation of gynecology and obstetrics(FIGO)staging,phase I,phase II,phase III and IV,respectively 83 cases,11 cases,12 cases,2 cases,and intraoperative frozen check for stage I,stageⅡ,Ⅲperiod,Ⅳcoincidence rate was 69.88%(58/83),72.73%(8/11),83.33%(10/12),100.0%(2/2),the total coincidence rate was 72.22%(78/108).According to the Grade(G)of tumor cells,78 cases were G1(72.22%),12 cases were G2(11.11%),and 18 cases were G3(16.67%).At the same time,the comparison between paraffin section and rapid freezing pathology examination was statistically significant(P<0.05).Conclusion Rapid freezing pathological examination has low accuracy in the diagnosis of histological grade in endometrial carcinoma,but it has high accuracy in the muscular infiltration depth,especially≥1/2 muscular infiltration depth,which can be used as an examination metho
作者
谢鹤英
虞杰
XIE Heying;YU Jie(Xiangcheng People's Hospital,Suzhou,Jiangsu 215131,China)
出处
《大医生》
2020年第22期121-123,共3页
Doctor
关键词
子宫内膜癌
病理检查
快速冰冻
诊断价值
endometrial carcinoma
pathological examination
rapid freezing
diagnostic value
