摘要
目的:探讨蒲地蓝配合揿针治疗小儿颈部淋巴结炎对C-反应蛋白(C-reactive protein,CRP)表达的影响。方法:2017年8月到2019年6月选择在本院诊治的小儿颈部淋巴结炎84例作为研究对象,根据随机数字表法把患儿分为联合组与对照组各42例。对照组给予蒲地蓝治疗,联合组给予蒲地蓝配合揿针治疗,疗程都为14 d,记录治疗效果与CRP表达变化情况。结果:治疗后联合组的总有效率为97.6%,显著高于对照组的85.7%(P<0.05)。联合组的局部消肿时间、局部压痛消退时间、发热消退时间都显著少于对照组(P<0.05)。两组治疗后的血清CRP值低于治疗前,联合组低于对照组,对比差异都有统计学意义(P<0.05)。两组治疗后的CD4+T淋巴细胞比例都高于治疗前,联合组高于对照组,对比差异都有统计学意义(P<0.05),两组治疗前后CD8+T淋巴细胞比例对比差异无统计学意义(P>0.05)。结论:蒲地蓝配合揿针治疗小儿颈部淋巴结炎能抑制CRP的释放,提高小儿的免疫功能,从而促进临床症状的消失,提高总体治疗效果。
Objective: To investigate the effecst of Pudilan combined with acupuncture on cervical lymphadenitis in children on the expression of C-reactive protein(CRP). Methods: From August 2017 to June 2019, 84 cases children with cervical lymphadenitis diagnosed and treated in our hospital were selected as the research object. All the cases were divided into the combined group and control group of 42 cases in each groups accorded to the random number table method. The control group were given Pudilland treatment, and the combined group were given Pudilland combined with acupuncture treatment for 14 days. The treatment effects and CRP expression changes were recorded. Results: The total effective rates of the combined group were 97.6 % after treatment, which were significantly higher than 85.7 % of the control group(P<0.05). The local swelling time, local tenderness remission time and fever remission time in the combined group were significantly shorter than those in the control group(P<0.05). The serum CRP value of the two groups after treatment were lower than that before treatment, and the combined group were lower than that of the control group, compared the difference were statistically significant(P<0.05). After treatment, the proportion of CD4^+T lymphocytes in both groups were higher than before treatment, and the combined group were higher than the control group, compared the difference between the two groups were statistically significant(P<0.05). There were no significant difference in the proportion of CD8^+T lymphocytes between the two groups before and after treatment(P>0.05). Conclusion: Pudilland combined with acupuncture in the treatment of cervical lymphadenitis in children can inhibit the release of CRP and improve the immune function of children, thereby promote the disappearance of clinical symptoms and improve the overall treatment effects.
作者
朱越
王新悦
步伟全
高志妹
高艳
ZHU Yue;WANG Xin-yue;BU Wei-quan;GAO Zhi-mei;GAO Yan(Pediatrics,The Second Affiliated Hospital of Nanjing University of Chinese Medicine(Jiangsu Second Traditional Medicine Hospital),Nanjing,Jiangsu,210017,China;Tuina,The Second Affiliated Hospital of Nanjing University of Chinese Medicine(Jiangsu Second Traditional Medicine Hospital),Nanjing,Jiangsu,210017,China;Department of Pediatrics,Jiangsu Hospital of Integrated Chinese and Western Medicine,Nanjing,Jiangsu,210028,China)
出处
《现代生物医学进展》
CAS
2020年第23期4552-4555,4560,共5页
Progress in Modern Biomedicine
基金
江苏省中医药局科研项目(YB201819)。
关键词
蒲地蓝
揿针
小儿颈部淋巴结炎
C-反应蛋白
免疫功能
Pudilan
Needle acupuncture
Cervical lymphadenitis
Children
C-reactive protein
Immune function
