摘要
目的:探讨腹腔镜胃癌D_(2)根治术对胃癌患者肠道屏障功能及生存质量产生的影响。方法:选取胃癌患者96例作为研究对象,采用随机数字表法分为两组,每组各48例。对照组行传统开腹胃癌D_(2)根治手术,观察组行腹腔镜胃癌D_(2)根治术。两组术后均连续观察3个月。观察患者肠道屏障功能及生存质量。结果:术后3个月,观察组血浆D-乳酸浓度及二胺氧化酶浓度均低于对照组,GQOLI-74评分均高于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜胃癌D_(2)根治术可有效改善胃癌患者肠道屏障功能,提高患者生存质量。
Objective: To investigate the effects of laparoscopic D_(2) radical gastrectomy on the intestinal barrier function and quality of life in patients with gastric cancer. Methods: 96 patients with gastric cancer were randomly divided into 2 groups, each with 48 cases. The control group underwent traditional open D_(2) gastrectomy, and the observation group underwent laparoscopic D_(2) radical gastric gastrectomy. Both groups had been observed for 3 months after surgeries, and the patient’s intestinal barrier function and quality of life were compared. Results: Three months after operation, the concentration of plasma D-lactic acid and diamine oxidase of the observation group was lower than that of the control group, and the GQOLI-74 score was higher than that of the control group. The difference was statistically significant(P<0.05). Conclusion: Laparoscopic D_(2) radical gastrectomy can effectively improve the intestinal barrier function and quality of life of patients with gastric cancer.
作者
孔瑞磊
KONG Ruilei(Dept of Oncology,the People's Hospital of Qingfeng County,Puyang 457300,China)
出处
《华夏医学》
CAS
2020年第6期111-114,共4页
Acta Medicinae Sinica
关键词
胃癌
腹腔镜
胃癌D2根治术
肠道屏障功能
gastric cancer
laparoscopy
D2 radical gastrectomy of gastric cancer
intestinal barrier function
