摘要
目的:探讨用连续肾脏替代疗法(CRRT)治疗重症急性胰腺炎的效果。方法:选取2014年5月至2019年5月期间在云县人民医院住院治疗的300例重症急性胰腺炎患者作为研究对象。将这些患者随机分为研究组和参照组,每组各有150例患者。两组患者入院后,均对其进行综合治疗。在此基础上,用CRRT对研究组患者进行治疗。然后比较两组患者治疗的效果。结果:治疗后,研究组患者治疗的总有效率、血清钙的水平均高于参照组患者,P<0.05;其急性胰腺炎Ranson评分标准的评分、急性生理与慢性健康评分标准(APACHEⅡ)的评分、Balthazar CT分级评分系统的评分及血清乳酸、淀粉酶、白细胞的水平均低于参照组患者,P<0.05。结论:用CRRT治疗重症急性胰腺炎的效果较为理想,可有效地缓解患者的病情,改善其各项血清学指标的水平。
Objective:To investigate the effect of continuous renal replacement therapy(CRRT)in the treatment of severe acute pancreatitis.METHODS:A total of 300 patients with severe acute pancreatitis who were hospitalized in Yunxian People’s Hospital from May 2014 to May 2019 were selected as the subjects.These patients were randomly assigned to study group and control group with 150 patients in each group.After admission,patients in both groups received comprehensive treatment.On this basis,patients in the study group were treated with CRRT.Then the treatment effect of the two groups was compared.RESULTS:After treatment,the total effective rate and serum calcium level of the study group were higher than those of the reference group(P<0.05);The ratings of Ranson score standard of acute pancreatitis,acute physiology and chronic health evaluation(APACHEⅡ)standard of grading,Balthazar CT grading evaluation system a nd the level of serum lactic acid,amylase,leukocyte were lower than the control group patients(P<0.05).Conclusion:CRRT has an ideal effect in the treatment of severe acute pancreatitis,which can effectively alleviate the patient’s condition and improve the level of various serological indexes.
作者
宗克仁
郑和
赵永光
杨明晶
ZONG Keren;ZHENG He;ZHAO Yongguang;YANG Mingjing(Department of Intensive Care,Yunxian People’s Hospital of Yunnan Provin ce,Yunxian 675800)
关键词
重症急性胰腺炎
连续肾脏替代疗法
疾病危重程度评分
血清学指标
Severe acute pancreatitis
Continuous renal replacement therapy
Disease severity score
Serological indicators
