摘要
In the present time, coronavirus disease COVID-19 has become prevalent across the globe and declared as a pandemic by the world health organization(WHO) [1]. As of now, many vaccines and medicines are in the approval process or at different stages of preclinical investigations to coup with the COVID-19 [2]. Coronavirus has a spike protein, which tends to bind with receptors present in the lung tissues, and that helps in its entry to the cells and replication inside [3]. Therefore, we are in need to design the multivalent nanomaterials, which can act as receptors to bind with spike protein of virus and stop its replication(Fig. 1).
作者
Manzar Abbas
Muhammad Ovais
Chunying Chen
Manzar Abbas;Muhammad Ovais;陈春英(Institute for Molecules and Materials,Radboud University,Nijmegen 6525 AJ,the Netherlands;CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,CAS Center for Excellence in Nanoscience,National Center for Nanoscience and Technology,Beijing 100190,China;Center of Materials Science and Optoelectronics Engineering,University of Chinese Academy of Sciences,Beijing 100049,China;GBA Research Innovation Institute for Nanotechnology,Guangzhou 510700,China)
基金
financial support from the European Union’s Horizon 2020 program under grant 839177 (PEPREP)
financial support from the Ministry of Science and Technology of China (2016YFA0201600, 2016YFE0133100)
the Science Fund for Creative Research Groups of the National Natural Science Foundation of China (11621505)。
