摘要
目的探究右美托咪定与丙泊酚对外科术后机械通气患者镇静效果及血流动力学的影响。方法将我院60例外科手术后机械通气患者作为研究对象,电脑随机将其分成右美托咪定组和丙泊酚组,各30例。右美托咪定组给予右美托咪定治疗,丙泊酚组给予丙泊酚治疗,比较两种方法的镇静效果及对血流动力学的影响。结果镇静30 min后,两组的Ramsay镇静评分对比差异无统计学意义(Z=1.23,P>0.05);右美托咪定组心动过缓(6.67%)、低血压(13.33%)、低血压合并心动过缓(3.33%)发生率分别低于丙泊酚组(30.00%、36.67%、26.67%),两组间对比差异有统计学意义(χ^(2)分别为5.45、4.36、6.41,P均<0.05)。结论给予外科术后机械通气患者右美托咪定或丙泊酚,均有更好的镇静效果,但右美托咪定对于血流动力学的影响较小,更适用于机械通气患者。
Objective To explore the effect of dexmedetomidine and propofol on sedation and hemodynamics of patients with postoperative mechanical ventilation.Methods A total of 60 patients with mechanical ventilation after surgery in a hospital were randomly divided into a dexmedetomidine group and a propofol group,with 30 patients in each group.The dexmedetomidine group was treated with dexmedetomidine,and the propofol group was treated with propofol.The sedative effect and hemodynamics of the two groups were compared.Results After 30 minutes of sedation,there was no statistically significant difference in Ramsay sedation scores between the two groups(Z=1.23,P>0.05).The incidence rates of bradycardia(6.67%),hypotension(13.3 3%),and hypotension combined with bradycardia(3.33%) in the dexmedetomidine group were lower than those in the propofol group(30.00%,36.67%,and 26.67% respectively),and the differences between the two groups were statistically significant(χ^(2)=5.45,4.36,6.41,all P<0.05).Conclusion Dexmedetomidine or propofol has a better sedative effect in postoperative patients with mechanical ventilation,but dexmedetomidine has less effect on hemodynamics and is more suitable for patients with mechanical ventilation.
作者
范风江
李波
冯丽霞
FAN Feng-jiang;LI Bo;FENG Li-xia(Comprehensive ICU of the First People's Hospital of Nanyang City,Nanyang 473010,Henan,China)
出处
《中国校医》
2021年第1期52-53,56,共3页
Chinese Journal of School Doctor
关键词
丙泊酚
右美托咪定
外科术后机械通气患者
镇静
血流动力学
propofol
dexmedetomidine
patients with mechanical ventilation after surgery
sedation
hemodynamics
