摘要
目的分析320层CT肺双入口灌注(DI-CTP)在肺癌患者术前评估中的应用。方法回顾性分析2019年5月至2020年5月我院收治并经病理学证实的300例肺癌患者的临床资料,均经320层CT肺DI-CTP扫描,测定动脉血流量(BF)、肺动脉血流量(PF)及灌注指数(PI),比较不同病理类型、TNM分期、肿瘤分化程度及有无淋巴结转移的BF、PF、PI值。结果腺癌、鳞癌及小细胞癌的BF、PF、PI值比较差异无统计学意义(P>0.05);T1-T4、N0-N2、M0-M1分期中PF、PI逐渐减小,BF升高,且T1-T4分期中BF、PF、PI比较差异具有统计学意义(P<0.05),N0-N2分期中PF、BF比较差异具有统计学意义(P<0.05),PI比较差异无统计学意义(P>0.05),M0-M1分期中PF比较差异具有统计学意义(P<0.05),BF、PI比较差异无统计学意义(P>0.05);肿瘤高、中分化的BF高于低、未分化(P<0.05);淋巴结转移的PAF、PI低于无淋巴结转移,BAF高于无转移淋巴结(P<0.05)。结论 320层CT肺DI-CTP可评估肺癌术前TNM分期、肿瘤分化程度和淋巴结有无远程转移,能够为治疗方案的制定提供参考。
Objective To analyze the application of 320-slice CT dual-in put CT perfusion(DI-CTP) in preoperative evaluation of lung cancer.Methods Clinical data of 300 patients with pathologically confirmed lung cancer who were treated at the hospital between May 2019 and May 2020 were retrospectively analyzed.All patients received 320-slice CT DI-CTP to determine arterial blood flow(BF),pulmonary artery blood flow(PF),and perfusion index(PI).BF,PF,and PI of patients with different pathological types,TNM stages,and differentiation degrees,and patients with and without lymph node metastasis were compared.Results Differences in BF,PF,and PI among patients with adenoca rcinoma,squamous cell carcinoma,and small cell carcinoma showed no statistical significance(P>0.05).PF and PI decreased,while BF increased in T1-T4,N0-N2,M0-M1 stages.Besides,differences in BF,PF and PI in T1-T4 stages,differences in PF and BF in N0-N2 stages were statistically significant(P<0.05).There was no statistically significa nt difference in PI(P>0.05).In M0-M1 stages,there were statistically significa nt differences in PF(P<0.05),but no statistically significa nt diffe rences in BF and PI(P>0.05).BF of patients with high and moderate differentiation was higher than that of patients with low differentiation or without differentiation(P<0.05).PAF and PI of patients with lymph node metastasis were lower,and BAF was higher than patients without(P<0.05).Conclusion 320-slice CT DI-CTP can be used to assess preoperative TNM staging,differentiation degree,and the presence or a bsence of dista nt lymph node metastasis of lung cancer to provide a reference for the formulation of treatment plans.
作者
胡述提
王铮
李伟
银瑞
HU Shu-ti;WANG Zheng;LI Wei;YIN Rui(Department of Thoracic Oncology,Nanyang Central Hospital,Nanyang 473000,Henan Province,China)
出处
《中国CT和MRI杂志》
2021年第3期58-61,共4页
Chinese Journal of CT and MRI
关键词
肺癌
320排CT
双入口灌注
术前评估
Lung Cancer
320-slice CT
Dual-input Perfusion
Preoperative Evaluation
