摘要
目的探讨胰腺癌患者检测幽门螺杆菌(Hp)感染的临床意义。方法选择2016年6—12月该院收治的25例胰腺癌患者(设为试验组),同期选择60名健康体检人员(设为对照组),采用C14呼气试验和免疫印迹法检测幽门螺杆菌。对两组检测结果进行分析比较。结果试验组Hp感染率72.00%与对照组45.00%相比,差异有统计学意义(χ^2=5.164,P<0.05);试验组患者CagA+VacA+Hp菌株感染率36.00%与CagA-VacA-Hp菌株感染率8.00%以及对照组CagA+VacA+Hp菌株感染率15.00%比较,差异有统计学意义(χ^2=4.045、4.662,P<0.05)。结论胰腺癌危险因素之一可能为Hp感染,特别是CagA+VacA+Hp菌株感染,其与胰腺癌之间的关系密切。
Objective To explore the clinical significance of detecting Helicobacter pylori(Hp)infection in patients with pancreatic cancer.Methods 25 patients with pancreatic cancer admitted to the hospital from June to December 2016(set as the experimental group)were selected,and 60 healthy medical examiners(set as the control group)were selected during the same period,and C14 breath test and western blotting detection of Helicobacter pylori were used.Analyzed and compared the test results of the two groups.Results The Hp infection rate of the experimental group was 72.00% compared with 45.00% of the control group,the difference was statistically significant(χ^2=5.164,P<0.05);compared with the CagA+VacA+Hp strain infection rate of 36.00% in the experimental group and the infection rate of CagA-VacA-Hp strains was 8.00%and the infection rate of CagA+VacA+Hp strains in the control group was 15.00%,which was statistically significant(χ^2=4.045,4.662,P<0.05).Conclusion One of the risk factors for pancreatic cancer may be Hp infection,especially CagA+VacA+Hp strain infection,which is closely related to pancreatic cancer.
作者
杨军雄
陆兆美
YANG Jun-xiong;LU Zhao-mei(Department of Gastroenterology,Guigang People's Hospital,Guigang,Guangxi Zhuang Autonomous Region,537100 China;Department of Neonatology,Guigang People's Hospital,Guigang,Guangxi Zhuang Autonomous Region,537100 China)
出处
《世界复合医学》
2020年第12期16-18,共3页
World Journal of Complex Medicine
关键词
胰腺癌
幽门螺杆菌
感染
Pancreatic cancer
Helicobacter pylori
Infection
